Catheterization of the gallbladder: A novel mouse model of severe acute cholangitis

Table 1 Primer sequences

Name	Symbol	Forward (5'-3')	Reverse (5'-3')
β-actin	ACTB	CCACCATGTACCCAGGCATT	AGGGTGTAAAACGCAGCTCA
IL-6	IL6	TACCACTTCACAAGTCGGAGGC	CTGCAAGTGCATCATCGTTGTTC
TNF-α	TNF	GGTGCCTATGTCTCAGCCTCTT	GCCATAGAACTGATGAGAGGGAG
IL-1β	IL-1β	TGGACCTTCCAGGATGAGGACA	GTTCATCTCGGAGCCTGTAGTG

Table 2 Data of laboratory examination at 24 h after the last operation (n = 6)

	Sham	LPS	BDL+LPS	BDL+CC	SAC
TBIL (mg/dL)	0.81 ± 0.15	1.26 ± 0.72	14.21 ± 2.10ac	13.35 ± 1.71ac	17.68 ± 2.66acef
ALT (IU/L)	18.63 ± 1.46	106.4 ± 20.24a	206.62 ± 25.92ac	197.48 ± 30.85ac	403.07 ± 74.92acef
AST (IU/L)	126.12 ± 34.39	558.97 ± 111.35a	1693.17 ± 313.73ac	1462.85 ± 397.75ac	2332.32 ± 531.64acef
γ-GGT (U/L)	11.17 ± 2.27	24.67 ± 4.96a	69.33 ± 9.74ac	70.00 ± 7.24ac	83.17 ± 9.08acef
ALP (U/L)	114.33 ± 19.68	229.67 ± 27.51a	2765.33 ± 250.51ac	2544.17 ± 350.24ac	3470.83 ± 522.35acef
Creatinine (mg/dL)	0.27 ± 0.04	0.35 ± 0.07	0.32 ± 0.08	0.31 ± 0.08	0.45 ± 0.09aef
BUN (mg/dL)	20.18 ± 5.43	25.77 ± 4.52	26.82 ± 7.80	25.17 ± 5.04	42.78 ± 9.76acef

Values are expressed as mean ± SD.

^aP < 0.05 vs sham group,

^cP < 0.05 vs LPS group,

^eP < 0.05 vs BDL + LPS group,

^fP < 0.05 vs BDL + CC group.