Rare type of pancreatitis as the first presentation of anti-neutrophil cytoplasmic antibody-related vasculitis

Table 1 Cases presented for pancreatic lesion in anti-neutrophil cytoplasmic antibody-related vasculitis

Authors	Year	Age (yr), sex	Symptoms	Pancreatic enzyme	ANCA	Vasculitis	Pancreatic lesionImaging	Diagnostic method	Other organ disorder	TreatmentPancreasOther organ	OutcomePancreasOther organ
O'Neil et al[8]	1992	44, M	Jaundice	ND	+	GPA	Ph tumor susp	Renal biopsy	Kidney Nose	Treated	Alive
							US: hypoechoic			PSL, CYC	Improved
							CT: 3 cm mass			PSL, CYC	Improved
Stuckey et al[9]	1992	45, M	Epigastric pain	AMY: 55	-	GPA	Pancreatitis susp	Parotid gland biopsy	Lung	Treated	Alive
			Nausea				CT:enlargement, sporadic			Conservative	Improved
							low density lesions			PSL, CYC	Improved
Berney et al[10]	1997	32, M	Epigastric pain	Raised of AMY, Lipase	PR3	MPA	Pancreatitis susp	Renal biopsy	Kidney	Treated	Alive
							CT: edematous			Conservative	Improved spontaneously
										PSL, CYC	Improved
Matsubayashi et al[11]	2001	65, M	Left abdominal pain	Trypsin: 550	PR3	GPA	Pbt tumor susp	Autopsy	Kidney Lung	None	Died
				Elastase-I: 440			CT: enlargement, sporadic		Spleen	None	Necrotizing pancreatitis
							low density lesions			None	Hemorrhagic pneumonia
Christl et al[12]	2004	55, F	Abdominal pain	ND	PR3	GPA	Pt tumor susp CT:	Postoperative pathology Renal biopsy	Kidney	Treated	Alive
			Weight loss				enlargement, sporadic			Ope	Improved
							low density lesions			PSL, CYC	Improved
Iwasa et al[13]	2005	84, F	Hematuria	N.D.	MPO	MPA	Normal	Autopsy	Kidney Lung	Treated	Died
			Fever							PSL	Necrotizing pancreatitis
										PSL	Lung hemorrhage
Haraguchi et al[14]	2005	84, F	Fever	AMY: 130	MPO	MPA	Normal	Autopsy	Kidney	Treated	Died
									Lung	PSL	Necrotizing pancreatitis
										PSL	Lung hemorrhage
Tinazzi et al[15]	2007	48, F	Epigastric pain	N.D.	-	GPA	Ph tumor susp	Postoperative pathology	-	Treated	Alive
							US: 2cm, mass, hypoechoic			Ope, PSL, CYC, MTX	Improved
							MRCP: obstruction of MPD			-	-
Joshipura et al[16]	2007	47, M	Epigastric pain Fever	AMY: 874 Lipase: 1294	PR3	GPA	Pancreatitis susp	Turbinate biopsy	Nose	Treated	Alive
							CT: Pbt edematous			PSL, CYC	Improved
										PSL, CYC	Improved
Abu-Hilal et al[17]	2008	20, F	Epigastric pain	Normal	PR3	GPA	Pancreatitis susp CT: Pt	Renal biopsy	Kidney	Treated	Died
									Lung Skin	Conservative	Improved spontaneously
			Nausea
							edematous		Intestine	PSL, CYC	Lung
											hemorrhage
Chawla et al[18]	2011	60, F	Epigastric pain	Lipase: 1316	PR3	GPA	Pancreatitis susp	Renal biopsy	Kidney	Treated	Alive
			Nausea				CT: diffusely edematous,		Lung	Conservative	Improved spontaneously
							Ph hypo attenuated lesion		Heart	PSL, CYC, AZA	Improved
Valerieva et al[19]	2013	62, F	Epigastric pain	Normal	PR3	GPA	Pt tumor susp	Postoperative	-	Treated	Alive
							CT: Pt, 3cm, mass	pathology		Ope, PSL, AZA	Improved
										-
Iida et al (this case)	2015	72, M	Weight loss	Trypsin: 723	MPO	MPA	Pancreatitis susp	Labo data	Kidney	Treated	Died
							CT: enlargement, multiple	Imaging	Lung	Conservative	Improved spontaneously
							hypo attenuated lesions	Vater biopsy		PSL, CYC	Lung hemorrhage

ANCA: Anti-neutrophil cytoplasmic antibody; ND: No data; AMY: Amylase; Ph: Pancreas head; Pbt: Pancreas body and tail; Pt: Pancreas tail; MRCP: Magnetic resonance cholangiopancreatography; MPD: Main pancreatic duct; PSL: Prednisolone; CYC: Cyclophosphamide; Ope: Operation; MTX: Methotrexate AZA: Azathioprine; M: Male; F: Female.