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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Feb 21, 2016; 22(7): 2383-2390
Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2383
Published online Feb 21, 2016. doi: 10.3748/wjg.v22.i7.2383
Rare type of pancreatitis as the first presentation of anti-neutrophil cytoplasmic antibody-related vasculitis
Tomoya Iida, Takeya Adachi, Suguru Nakagaki, Takashi Yabana, Akira Goto, Yoshihiro Kondo, Department of Gastroenterology, Otaru City General Hospital, Otaru, Hokkaido 047-8550, Japan
Tetsuya Tabeya, Department of Internal Medicine of Connective Tissue Disease, Otaru City General Hospital, Otaru, Hokkaido 047-8550, Japan
Kiyoshi Kasai, Department of Diagnostic Pathology, Otaru City General Hospital, Otaru, Hokkaido 047-8550, Japan
Author contributions: All authors helped to perform the research; Iida T wrote the paper; all authors have approved the final draft of the manuscript.
Supported by Otaru City General Hospital, Otaru, Hokkaido, Japan
Institutional review board statement: Otaru City General Hospital Institutional Review Board for Conduction and Submission of the study.
Informed consent statement: The patient provided informed consent prior to study enrollment.
Conflict-of-interest statement: To the best of our knowledge, no conflict of interest, financial or other, exists for any authors listed in this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Tomoya Iida, MD, Department of Gastroenterology, Otaru City General Hospital, 1-1 1-chome, Wakamatu-cho, Otaru, Hokkaido 047-8550, Japan. tomoya.iida.0306@gmail.com
Telephone: +81-134-251211 Fax: +81-134-326424
Received: July 22, 2015
Peer-review started: July 30, 2015
First decision: August 28, 2015
Revised: September 11, 2015
Accepted: December 12, 2015
Article in press: December 12, 2015
Published online: February 21, 2016
Processing time: 192 Days and 19.7 Hours
Peer-review started: July 30, 2015
First decision: August 28, 2015
Revised: September 11, 2015
Accepted: December 12, 2015
Article in press: December 12, 2015
Published online: February 21, 2016
Processing time: 192 Days and 19.7 Hours
Core Tip
Core tip: Pancreatic lesions in anti-neutrophil cytoplasmic antibody (ANCA)-related vasculitis are very rare. Only few cases of pancreatic lesions in ANCA-related vasculitis have been reported previously. We encountered a case presenting with pancreatic enlargement and a diffuse, poorly enhanced area in the pancreas during the early stages of ANCA-related vasculitis. In light of the clinical course, it appears that factors such as thrombus formation caused by the vasculitis during the early stages of ANCA-related vasculitis cause abnormal distribution of pancreatic blood flow, resulting in non-uniform pancreatitis manifested in the imaging findings.