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©The Author(s) 2016.
World J Gastroenterol. Nov 14, 2016; 22(42): 9411-9418
Published online Nov 14, 2016. doi: 10.3748/wjg.v22.i42.9411
Published online Nov 14, 2016. doi: 10.3748/wjg.v22.i42.9411
Table 1 Demographic, clinical and laboratory parameters of Crohn’s disease and primary intestinal lymphoma patients n (%)
Parameters | CD | PIL | P value | Score |
n = 85 | n = 56 | |||
Gender (male/female) | 48/37 | 32/24 | 0.937 | N/A |
Age of onset | 32.0 ± 9.9 | 52.8 ± 16.3 | < 0.001 | 1 |
Height (cm) | 166.1 ± 6.6 | 164.6 ± 7.3 | 0.189 | N/A |
Weight (kg) | 59.3 ± 9.4 | 57.7 ± 10.2 | 0.346 | N/A |
Symptom duration (mo) | 16 (11-19) | 2 (1-6) | < 0.001 | -1 |
Abdominal pain | 64 (75.3) | 39 (69.6) | 0.459 | N/A |
Diarrhea | 60 (70.6) | 15 (26.8) | < 0.001 | 1 |
Abdominal distension | 29 (34.1) | 21 (37.5) | 0.681 | N/A |
Nausea | 12 (14.1) | 13 (23.2) | 0.166 | N/A |
Hematochezia | 22 (25.9) | 11 (19.6) | 0.392 | N/A |
Fever | 13 (15.3) | 15 (26.8) | 0.094 | N/A |
Weight loss | 42 (49.4) | 32 (57.1) | 0.368 | N/A |
Abdominal mass | 5 (5.9) | 9 (16.1) | 0.048 | -1 |
Perianal lesions | 37 (43.5) | 2 (3.6) | < 0.001 | 1 |
History of GI surgery | 12 (14.1) | 4 (7.1) | 0.189 | N/A |
Perforation | 4 (4.7) | 5 (8.9) | 0.515 | N/A |
Extraintestinal manifestation | 6 (7.1) | 2 (3.6) | 0.614 | N/A |
Hemoglobin(g/L) | 106.9 ± 17.8 | 109.7 ± 22.4 | 0.408 | N/A |
Hematocrit | 35.1 ± 3.9 | 33.9 ± 5.7 | 0.127 | N/A |
Platelet (1 × 109/L) | 263.7 ± 96.2 | 261.2 ± 116.5 | 0.890 | N/A |
Albumin (g/L) | 29.7 ± 6.1 | 31.3 ± 7.0 | 0.151 | N/A |
Elevated ESR | 53 (62.4) | 28 (50.0) | 0.147 | N/A |
Elevated CRP | 59 (69.4) | 31 (55.4) | 0.089 | N/A |
Elevated lactate dehydrogenase | 2 (2.4) | 8 (14.3) | 0.018 | -1 |
Elevated serum β2-microglobulin | 0 (0.0) | 12 (21.4) | < 0.001 | -1 |
Table 2 Endoscopic parameters of Crohn’s disease and primary intestinal lymphoma patients n (%)
Parameters | CD | PIL | P value | Score |
n = 85 | n = 56 | |||
Multiple-site lesions | 73 (85.9) | 19 (33.9) | < 0.001 | 1 |
Pseudo-polyp formation | 26 (30.6) | 10 (17.9) | 0.090 | N/A |
Aphthoid ulcer | 37 (43.5) | 21 (37.5) | 0.477 | N/A |
Longitudinal ulcer | 69 (81.2) | 5 (8.9) | < 0.001 | 1 |
Irregular ulcer | 31 (36.5) | 32 (57.1) | 0.016 | -1 |
Intraluminal proliferative mass | 11 (12.9) | 31 (55.4) | < 0.001 | -1 |
Bowel stricture | 27 (31.8) | 15 (26.8) | 0.527 | N/A |
Anorectal involvement | 13 (15.3) | 4 (7.1) | 0.146 | N/A |
Table 3 Computed tomography enterography parameters of Crohn’s disease and primary intestinal lymphoma patients n (%)
Parameters | CD | PIL | P value | Score |
n = 85 | n = 56 | |||
Involvement of ≤ 3 segments | 31 (36.5) | 45 (80.4) | < 0.001 | -1 |
Circular thickening of bowel wall | 33 (38.8) | 35 (62.5) | 0.006 | -1 |
Wall thickness of > 8 mm | 21 (24.7) | 45 (80.4) | < 0.001 | -1 |
Aneurysmal dilation | 5 (5.9) | 27 (48.2) | < 0.001 | -1 |
Target sign | 25 (29.4) | 12 (21.4) | 0.292 | N/A |
Enhancement after a contrast-enhanced scan | 67 (78.8) | 37 (66.1) | 0.092 | N/A |
Stricture with proximal dilation | 19 (22.4) | 4 (7.1) | 0.017 | 1 |
Abscess | 7 (8.2) | 2 (3.6) | 0.449 | N/A |
Phlegmon | 8 (9.4) | 2 (3.6) | 0.324 | N/A |
Ascites | 5 (5.9) | 7 (12.5) | 0.174 | N/A |
“Comb sign” | 61 (71.8) | 18 (32.1) | < 0.001 | 1 |
Enlargement of the abdominal lymph nodes | 42 (49.4) | 36 (64.3) | 0.082 | N/A |
Enhanced density of the peri-intestinal fat | 30 (35.3) | 26 (46.4) | 0.186 | N/A |
Mass showing the “sandwich sign” | 2 (2.4) | 9 (16.1) | < 0.001 | -1 |
Intussusceptions | 0 (0.0) | 3 (5.4) | 0.031 | -1 |
- Citation: Zhang TY, Lin Y, Fan R, Hu SR, Cheng MM, Zhang MC, Hong LW, Zhou XL, Wang ZT, Zhong J. Potential model for differential diagnosis between Crohn's disease and primary intestinal lymphoma. World J Gastroenterol 2016; 22(42): 9411-9418
- URL: https://www.wjgnet.com/1007-9327/full/v22/i42/9411.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i42.9411