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Copyright ©The Author(s) 2016.
World J Gastroenterol. Sep 14, 2016; 22(34): 7760-7766
Published online Sep 14, 2016. doi: 10.3748/wjg.v22.i34.7760
Table 1 Development of pancreatic stone formation and functional impairment in autoimmune pancreatitis patients during long-term follow-up
Ref.YearFollow-up period (mo)Incident rate
Pancreatic stoneEndocrine dysfunctionEndocrine dysfunction
Uchida et al[15]2006414.8% (1/21)60.0% (6/10)46.2% (6/13)
Maire et al[23]201150NA34.1% (15/44)38.6% (17/44)
Maruyama et al[14]20129140.6% (28/69)NANA
Hart et al[12]2013NA7.0% (46/659)NANA
Hirano et al[13]20137611.3% (8/71)NANA
Buijs et al[24]201575NA82.4% (56/68)56.1% (37/66)
Table 2 Characteristics of the autoimmune pancreatitis patients with pancreatic cancer whose clinical data were available
CaseRef.YearAgeSexSmokingAlcoholDiabetesLocation of the PCPeriod onset of AIP to PC
1Inoue et al[39]200662MYesNoYesBody0 (Synchronous)
2Ghazale et al[40]200772MNANANABody60
3Witkiewicz et al[41]200880MNANANAHead0 (Synchronous)
4Motosugi et al[42]200959MNANAYesBody and tail0 (Synchronous)
5Matsubayashi et al[43]200965MNoNoNoNA0 (Synchronous)
6Gupta et al[48]201273MNANANATail120
7Gupta et al[48]201269MNANANAHead60
8Hirano et al[47]201458MNoNAYesNA119
9Hirano et al[47]201470MNoNAYesNA162
10Ikeura et al[46]201461FYesNoNoHead31
11Ikeura et al[46]201439FNoNoNoBody186
12Ikeura et al[46]201480MNoNoYesHead67
Table 3 Development of cancer at or after autoimmune pancreatitis diagnosis
Ref.YearFollow-up period (mo)Incident rate of PCIncident rate of extrapancreatic cancer
Nishino et al[27]2006410.0% (0/12)16.7% (2/12)
Takuma et al[50]2011400.0% (0/50)NA
Yamamoto et al[51]2012370.0% (0/106)110.1% (11/106)1
Shiokawa et al[52]2012400.0% (0/108)13.9% (15/108)
Hart et al[12]2013NA0.7% (5/659)7.0% (46/659)
Gupta et al[48]2013492.4% (2/84)NA
Hart et al[49]2014430.9% (1/116)9.5% (11/116)
Huggett et al[37]2014330.9% (1/115)27.0% (8/115)2
Hirano et al[47]2014732.1% (2/95)11.5% (13/113)1
Ikeura et al[46]2014624.8% (3/63)3.2% (2/63)
Shimizu et al[45]2015541.2% (1/84)11.9% (8/84)
Buijs et al[24]2015750.0% (0/68)11.8% (8/68)