Copyright
©The Author(s) 2016.
World J Gastroenterol. Jun 7, 2016; 22(21): 5042-5049
Published online Jun 7, 2016. doi: 10.3748/wjg.v22.i21.5042
Published online Jun 7, 2016. doi: 10.3748/wjg.v22.i21.5042
Table 1 Immunohistochemical expression of matrix metalloprotein 9 and vascular endothelial growth factor in hepatocellular carcinoma (%) in groups A and B
Group | TACE + GRGDSP | TACE + GRGDSP loaded nanoparticles | P value | |||||||||||
Score | 0 | 1 | 2 | 3 | 4 | 5 | 0 | 1 | 2 | 3 | 4 | 5 | ||
VEGF | Tumor | 3 | 13 | 28 | 20 | 20 | 16 | 29 | 5 | 18 | 20 | 18 | 10 | 0.000 |
MMP-9 | Tumor | 0 | 1 | 17 | 18 | 42 | 22 | 0 | 6 | 36 | 41 | 12 | 5 | 0.000 |
Table 2 Immunohistochemical expression of matrix metalloprotein 9 and vascular endothelial growth factor in hepatocellular carcinoma (%) in groups A and C
Group | TACE | TACE + GRGDSP loaded nanoparticles | P value | |||||||||||
Score | 0 | 1 | 2 | 3 | 4 | 5 | 0 | 1 | 2 | 3 | 4 | 5 | ||
VEGF | Tumor | 0 | 2 | 10 | 11 | 16 | 61 | 29 | 5 | 18 | 20 | 18 | 10 | 0.000 |
MMP-9 | Tumor | 0 | 6 | 4 | 0 | 9 | 81 | 0 | 6 | 36 | 41 | 12 | 5 | 0.000 |
- Citation: Qian J, Oppermann E, Tran A, Imlau U, Qian K, Vogl TJ. Transarterial administration of integrin inhibitor loaded nanoparticles combined with transarterial chemoembolization for treating hepatocellular carcinoma in a rat model. World J Gastroenterol 2016; 22(21): 5042-5049
- URL: https://www.wjgnet.com/1007-9327/full/v22/i21/5042.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i21.5042