Basic Study
Copyright ©The Author(s) 2016.
World J Gastroenterol. May 7, 2016; 22(17): 4330-4337
Published online May 7, 2016. doi: 10.3748/wjg.v22.i17.4330
Table 1 Evaluation of pancreatic lesions
Parameter/lesionGrade 0Grade 1Grade 2Grade 3
EdemaAbsentDiffuse dilation of interlobular septiDiffuse dilation of interacinous spaceDiffuse dilation of intercellular space
VacuolizationAbsentFocal (< 25%)Diffuse (25%-50%)Severe (> 50%)
NecrosisAbsent< 50% lobules50%-75% lobules> 75% lobules
Vessels congestionAbsentFocal (< 25%)Diffuse (25%-50%)Severe (> 50%)
InflammationAbsent< 50% lobules50%-75% lobules> 75% lobules
Table 2 Within group comparison of serum levels (mean ± SD) of biochemical markers (amylase, lipase and CRP) at different sampling points (Basal, End of endoscopy and 24 h later)
GroupTimeAmylase (IU/L)Lipase (IU/L)CRP (mg/L)
GPBasal2507.9 ± 553.6134.3 ± 19.26130.1 ± 43.31
End2317 ± 523.5245.4 ± 33.6127.4 ± 41.71
24 h3993.3 ± 2047.33444.6 ± 417.22,d182.3 ± 44.52,d
GP + DBEBasal2214.9 ± 385.9119.6 ± 16.4120.6 ± 26.41
End1920.2 ± 360.8237.1 ± 29.52,b16.2 ± 21.81
24 h2717.2 ± 686.62146.8 ± 128.11,2117.3 ± 46.12,d
GDBEBasal1968.1 ± 929.6117.7 ± 7.7139.1 ± 41.21
End1850 ± 820.728.8 ± 3.6137.2 ± 38.31
24 h2487.2 ± 1093.4226.7 ± 20.91114.8 ± 100.72,d
GCBasal1965.4 ± 856.4110.7 ± 3.119.8 ± 8.81
End1881.9 ± 839.519.1 ± 2.32110.1 ± 8.31
24 h2245.8 ± 995.9137.5 ± 23.6124.2 ± 17.41
Table 3 Comparison of histopathological features (mean ± SD) between the GP, GP + DBE groups according to the categorization scale given in Table 1
GroupEdemaVacuolizationNecrosisVessels congestionInflammation
GP3.38 ± 0.662.95 ± 0.8311.59 ± 0.7510.89 ± 0.440.21 ± 0.51
GP + DBE3.29 ± 0.642.56 ± 0.971.32 ± 0.750.93 ± 0.410.21 ± 0.56
Table 4 Significance levels for the χ2 test of association between the experimental procedures (GP, GP + DBE) and the frequency of damaged samples
Histopathological parameterP value
Edema0.73
Vacuolization0.061
Necrosis0.091
Vessels congestion0.80
Inflammation0.46