Tolerability of magnifying narrow band imaging endoscopy for esophageal cancer screening

Table 1 Patient characteristics

Clinical parameters	NBI (n = 25)	Lugol (n = 26)	P value
Age, yr	60 ± 11	61 ± 8	0.597
Male/female, n	25/0	25/1	1.000
HRA-F score	8 ± 1	8 ± 1	0.277
Past history of head and neck cancer, n	0	1	1.000
Previous EGD, times	4 ± 3	3 ± 2	0.475

Values are mean ± SD unless otherwise noted. The HRA-F score was made from an HRA model for esophageal cancer that includes a questionnaire about alcohol flushing[5]. EGD: Esophagogastroduodenoscopy; HRA-F: Health risk appraisal-flushing; NBI: Narrow band imaging.

Table 2 Change in vital signs and procedure time

Variables	NBI (n = 25)	Lugol (n = 26)	P value
Increase in SBP after procedure (> 20 mmHg), n	6	8	0.755
Increase in DBP after procedure (> 20 mmHg), n	1	5	0.190
Increase in HR after procedure (> 20 bpm), n	7	16	0.024
Decrease in SpO2 (> 3 %), n	1	3	0.609
Gag reflex, n	1	6	0.099
Total procedure time, second	450 ± 116	565 ± 174	0.004
Esophageal observation time, second	44 ± 26	151 ± 72	< 0.001

Values are mean ± SD unless otherwise noted. DBP: Diastolic blood pressure; HR: Heart rate; SBP: Systolic blood pressure.

Table 3 Biopsy results

Variables	NBI (n = 25)	Lugol (n = 26)	P value
Biopsy from esophageal lesion, n	1	6	0.099
Biopsy result, n
No atypia or LGIN	1	5
HGIN or SCC	0	1

HGIN: High grade intraepithelial neoplasia; LGIN: Low grade intraepithelial neoplasia; SCC: Squamous cell carcinoma.