Meta-Analysis
Copyright ©The Author(s) 2015.
World J Gastroenterol. Oct 28, 2015; 21(40): 11481-11488
Published online Oct 28, 2015. doi: 10.3748/wjg.v21.i40.11481
Table 1 Basic characteristics of the studies included in the systematic review
Ref.YearCountryStudy designPatients performing 18F-FDG-PET or PET/CT with GB lesionsMean age (yr)Gender (%male)
Koh et al[4]2003JapanNR166844%
Anderson et al[5]2004United StatesNR146557%
Rodríguez-Fernández et al[6]2004SpainNR166831%
Wakabayashi et al[7]2005JapanProspective307150%
Nishiyama et al[8]2006JapanRetrospective327037%
Oe et al[9]2006JapanRetrospective126866%
Petrowsky et al[10]2006SwitzerlandProspective14NRNR
Shukla et al[11]2008IndiaNR244533%
Corvera et al[12]2008United StatesRetrospective416252%
Furukawa et al[13]2008JapanRetrospective18NRNR
Furukawa et al[14]2009JapanRetrospective18NRNR
Butte et al[15]2009ChileProspective535720%
Lee et al[16]2010South KoreaRetrospective16NRNR
Zhu et al[17]2010United StatesNR10NRNR
Lee et al[18]2012South KoreaRetrospective206545%
Kumar et al[19]2012IndiaRetrospective495231%
Yamada et al[20]2012JapanRetrospective14NRNR
Albazaz et al[2]2013United KingdomRetrospective30NRNR
Lee et al[21]2013South KoreaRetrospective9NRNR
Onal et al[22]2013TurkeyRetrospective106370%
Ramos-Font et al[1]2014SpainProspective496843%
18F-FDG: Fluorine-18-fluorodeoxyglucose; PET: Positron emission tomography; CT: Computed tomography; NR: Not reported; GB: Gallbladder; GBCa: Gallbladder carcinoma.
Table 2 Technical characteristics of the studies included in the systematic review
Ref.YearDevice18F-FDG mean injected dose (MBq)Time between 18F-FDG injection and image acquisition (min)Image analysisOther imaging methods performed
Koh et al[4]2003PET18560VisualCT
Anderson et al[5]2004PET37060VisualCT, MRI
Rodríguez-Fernández et al[6]2004PET37045-60Visual and semiquantitativeUS, CT
Wakabayashi et al[7]2005PET18560VisualCT
Nishiyama et al[8]2006PET185-37040-55Visual and semiquantitativeUS, CT
Oe et al[9]2006PET3/kg62-146Visual and semiquantitativeUS, CT, MRI
Petrowsky et al[10]2006PET/CT37045Visual and semiquantitativeCT
Shukla et al[11]2008PET/CT37060VisualCT
Corvera et al[12]2008PET370-555NRVisual and semiquantitativeCT, MRI
Furukawa et al[13]2008PET200-25060VisualCT
Furukawa et al[14]2009PET200-25060Visual and SemiquantitativeCT, MRI, PTC
Butte et al[15]2009PET/CT37060Visual and semiquantitativeNR
Lee et al[16]2010PET/CT370-55560Visual and semiquantitativeCT
Zhu et al[17]2010PET or PET/TC370-55545Visual and SemiquantitativeCT
Lee et al[18]2012PET/CT37045-60VisualNR
Kumar et al[19]2012PET/CT5.5/kg60Visual and semiquantitativeNR
Yamada et al[20]2012PET4.5/kg60Visual and semiquantitativeNR
Albazaz et al[2]2013PET/CT40060Visual and semiquantitativeCT, MRI
Lee et al[21]2013PET/CT370-55560Visual and semiquantitativeCT, MRCP, ERCP, EUS
Onal et al[22]2013PET/CT370-55560Visual and SemiquantitativeMRI, CT
Ramos-Font et al[1]2014PET/CT37060Visual and semiquantitativeNR
18F-FDG: Fluorine-18-fluorodeoxyglucose; PET: Positron emission tomography; CT: Computed tomography; MR: Magnetic resonance; US: Ultrasonography; CR: Chest radiography; PTC: Percutaneous transhepatic cholangiography; NR: Not reported; CT: Computed tomography; ERCP: Endoscopic retrograde cholangiopancreatography.
Table 3 Diagnostic accuracy data of fluorine-18-fluorodeoxyglucose-positron emission tomography and positron emission tomography/computed tomography on a per patient-based analysis
Ref.YearOverall
PET
PET/CT
TPFPFNTNTPFPFNTNTPFPFNTN
Koh et al[4]200361276127NRNRNRNR
Anderson et al[5]200471247124NRNRNRNR
Rodríguez-Fernández et al[6]200442194219NRNRNRNR
Nishiyama et al[8]20061954419544NRNRNRNR
Oe et al[9]200631023102NRNRNRNR
Petrowsky et al[10]200614100NRNRNRNR14100
Corvera et al[12]20082414224142NRNRNRNR
Furukawa et al[13]20081701217010NRNRNRNR
Lee et al[16]201014020NRNRNRNR14020
Lee et al[18]2012166424NRNRNRNR166424
Yamada et al[20]201291409140NRNRNRNR
Albazaz et al[2]201315100NRNRNRNR15100
Ramos-Font et al[1]2014202015NRNRNRNR252022
NR: Not reported; IH-CCA: Intrahepatic cholangiocarcinoma; H-CCA: Hilar cholangiocarcinoma; EH-CCA: Extrahepatic cholangiocarcinoma; TP: True positive; FP: False positive; FN: False negative; TN: True negative.