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©The Author(s) 2015.
World J Gastroenterol. Aug 21, 2015; 21(31): 9394-9402
Published online Aug 21, 2015. doi: 10.3748/wjg.v21.i31.9394
Published online Aug 21, 2015. doi: 10.3748/wjg.v21.i31.9394
Table 1 Basic information on the study population
Factors | n (%) |
Age (yr), mean (SD) | 51.8 (12.4) |
Age > 65 yr | 102 (15.1) |
Male | 502 (79.2) |
ICG R15 | |
< 10% | 545 (86.8) |
10%-20% | 69 (10.9) |
20%-30% | 8 (1.3) |
30%-40% | 6 (0.9) |
> 40% | 6 (0.9) |
Hepatitis serology | |
Hepatitis B | 452 (71.3) |
Hepatitis C | 34 (5.4) |
Hepatitis B and C | 25 (3.9) |
Negative or not determined | 123 (19.4) |
Cirrhosis | 479 (75.5) |
Portal vein hypertention | 78 (12.3) |
Table 2 Preoperative biochemical indices and ratings n (%)
Serum albumin (g/L) | 41.1 (4.0) |
Platelet count (103/mm3) | 178.6 (75.1) |
Serum creatinine (μmol/L) | 67.7 (14.0) |
Serum total bilirubin (μmol/L) | |
Serum total bilirubin (μmol/L) | 6.3 (14.2) |
Serum sodium (mmol/L) | 142.0 (2.8) |
INR, mean (SD) | 1.04 (0.10) |
CTP score | |
Class A | 629 (98.2) |
Class B | 5 (0.8) |
MELD score, mean (SD) | 8.4 (1.5) |
Tumor size (cm) | 7.4 (4.9) |
Table 3 Relevant surgical indices n (%)
Operating time (min) | 251 (52) |
Porta hepatis clamping time (min) | 20 (11.2) |
Estimated blood loss (mL) | 438 (559.7) |
Extent of hepatectomy | |
Subsegmentectomy or limited resection | 262 (41.3) |
Segmentectomy | 163 (5.7) |
Bisegmentectomy | 90 (14.2) |
Major hepatectomy (3 or more segments) | 119 (18.8) |
Intraoperative RBC transfusion | |
Yes | 142 (22.4) |
No | 492 (77.6) |
Blocking methods | |
Portal vein blocking | 30 (4.7) |
Pringle maneuver | 392 (61.8) |
No | 212 (33.4) |
Table 4 Postoperative complications of hepatectomy
Overall morbidity | 44.90% |
Surgical morbidity | |
Posthepatectomy liver failure | 19% |
Biliary leakage | 40% |
Posthepatectomy hemorrhage | 7% |
Perihepatic abscess | 22% |
Wound infection | 42% |
Cholangitis | 5% |
Pleural effusion | 62% |
Portal vein thrombosis | 3% |
Medical morbidity | |
Respiratory insufficiency/failure | 12% |
Renal failure | 6% |
Pneumonia | 28% |
Cardiac arrhythmia | 20% |
Pulmonary embolism | 2% |
Cardiac failure | 8% |
Myocardial infarction | 5% |
Relaparotomy | 4% |
Table 5 Postoperative liver failure rate according to criteria
Criteria | Yes | No |
Swiss | 2.75% | 5.66% |
Japan | 2.62% | 6.56% |
Chinese | 2.73% | 16.67% |
Table 6 Multivariate logistic analysis of hepatic failure
Variables in the equation | Sig. |
Liver cirrhosis | 0.009 |
Bile leakage | 0.199 |
Ascites | 0.184 |
Abdominal infection | 0.014 |
Major hepatectomy | 0.006 |
Bleeding | 0.878 |
Height (cm) | 0.710 |
Weight (kg) | 0.361 |
HB (g/dL) | 0.819 |
BSA (m2) | 0.384 |
BMI (kg/m2) | 0.733 |
Kmin | 0.356 |
ICGR15 | 0.510 |
T12 (min) | 0.617 |
EHBF (L/min) | 0.472 |
Total hospital duration | 0.017 |
- Citation: Wang XQ, Liu Z, Lv WP, Luo Y, Yang GY, Li CH, Meng XF, Liu Y, Xu KS, Dong JH. Safety validation of decision trees for hepatocellular carcinoma. World J Gastroenterol 2015; 21(31): 9394-9402
- URL: https://www.wjgnet.com/1007-9327/full/v21/i31/9394.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i31.9394