Retrospective Study
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 21, 2015; 21(31): 9394-9402
Published online Aug 21, 2015. doi: 10.3748/wjg.v21.i31.9394
Safety validation of decision trees for hepatocellular carcinoma
Xian-Qiang Wang, Zhe Liu, Wen-Ping Lv, Ying Luo, Guang-Yun Yang, Chong-Hui Li, Xiang-Fei Meng, Yang Liu, Ke-Sen Xu, Jia-Hong Dong
Xian-Qiang Wang, Ke-Sen Xu, Jia-Hong Dong, Department of Hepatobiliary Surgery, Qilu Hospital, Shandong University, Jinan 250012, Shandong Province, China
Zhe Liu, Wen-Ping Lv, Ying Luo, Guang-Yun Yang, Chong-Hui Li, Xiang-Fei Meng, Yang Liu, Jia-Hong Dong, Department of Hepatobiliary Surgery, PLA General Hospital, Beijing 100853, China
Author contributions: Dong JH, Lv WP and Xu KS designed the research; Wang XQ and Liu Z performed the research; Li CH and Yang GY contributed new reagents and analytic tools; Liu Y and Meng XF analyzed the data; and Wang XQ and Luo Y wrote the paper.
Supported by Grants from the Project of the National Science and Technology Major Project, No. 2012BAI06B01; and Postdoctoral Science Foundation funded project, No. 201003781.
Institutional review board statement: The study was reviewed and approved by the PLA General Hospital Institutional Review Board.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflicting interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Correspondence to: Jia-Hong Dong, MD, PhD, FACS, Department of Hepatobiliary Surgery, PLA General Hospital, No. 28 Fuxing Road, Beijing 100853, China.
Telephone: +86-10-66938030 Fax: +86-10-66938030
Received: November 2, 2014
Peer-review started: November 2, 2014
First decision: December 2, 2014
Revised: March 11, 2015
Accepted: April 17, 2015
Article in press: April 17, 2015
Published online: August 21, 2015
Processing time: 290 Days and 16.6 Hours
Core Tip

Core tip: We have established a decision tree for safe hepatectomy based on four variables: normal or cirrhotic liver, Child-Turcotte-Pugh score, the indocyanine green retention rate at 15 min, and the ratio of reserved functional liver volume to standard liver volume. Post-hepatectomy liver failure (PHLF) has been identified by the “50-50” criteria. The Chinese consensus decision tree expands the indications for hepatic resection for liver tumor and does not increase the PHLF rate compared to the Swiss-Clavien and Tokyo University-Makuuchi decision trees. The Chinese consensus decision tree would be a safe and effective algorithm for hepatectomy in patients with liver tumor.