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©The Author(s) 2015.
World J Gastroenterol. Jul 21, 2015; 21(27): 8358-8365
Published online Jul 21, 2015. doi: 10.3748/wjg.v21.i27.8358
Published online Jul 21, 2015. doi: 10.3748/wjg.v21.i27.8358
Table 1 Characteristics of the early gastric cancer and advanced gastric cancer groups n (%)
| Overall | EGC group | AGC group | P value | |
| (n = 413) | (n = 184) | (n = 229) | ||
| Mean age (mean ± SD, yr) | 61.3 ± 11.6 | 62.1 ± 10.2 | 60.8 ± 12.6 | 0.263 |
| Gender | ||||
| Male | 293 (70.9) | 137 (74.5) | 156 (68.1) | 0.159 |
| Female | 120 (29.1) | 47 (25.5) | 73 (31.9) | |
| Smoking | 229 (55.4) | 110 (59.8) | 109 (47.6) | 0.014 |
| Alcohol | 190 (46.0) | 97 (52.7) | 93 (40.6) | 0.014 |
| H. pylori infection | 258 (62.5) | 105 (57.1) | 153 (66.8) | 0.042 |
| Histology | ||||
| Differentiated | 262 (63.4) | 184 (100) | 78 (34.1) | < 0.001 |
| Undifferentiated | 151 (36.6) | 0 | 151 (65.9) | |
| Follow-up duration (mean ± SD, months) | 37.2 ± 15.9 | 36.9 ± 14.9 | 37.4 ± 16.7 | 0.697 |
Table 2 Incidence of second primary cancers in gastric cancer patients n (%)
| Overall | EGC group | AGC group | P value | |
| (n = 413) | (n = 184) | (n = 229) | ||
| Second primary cancer | 38 (9.2) | 17 (9.2) | 21 (9.2) | 0.981 |
| Synchronous cancer | 18 (4.4) | 8 (4.3) | 10 (4.4) | 0.993 |
| Metachronous cancer | 20 (4.8) | 9 (4.9) | 11 (4.8) | 0.967 |
Table 3 Distribution of second primary cancers according to gastric cancer group n (%)
| Location | Overall | EGC group | AGC group |
| (n = 38) | (n = 17) | (n = 21) | |
| Lung | 7 (18.4) | 3 (17.6) | 4 (19.0) |
| Colorectal | 5 (13.2) | 2 (11.8) | 3 (14.3) |
| Esophagus | 5 (13.2) | 2 (11.8) | 3 (14.3) |
| Urogenital | 4 (10.5) | 2 (11.8) | 2 (9.5) |
| Gynecologic | 3 (7.9) | 1 (5.9) | 2 (9.5) |
| Pancreas | 3 (7.9) | 1 (5.9) | 2 (9.5) |
| Skin | 2 (5.3) | 1 (5.9) | 1 (4.8) |
| Hematology | 2 (5.3) | 1 (5.9) | 1 (4.8) |
| Others | 7 (18.3) | 4 (23.4) | 3 (14.3) |
Table 4 Logistic regression analysis of risk factors in the early gastric cancer group
| Synchronous cancer | Metachronous cancer | |||
| OR (95%CI) | P value | OR (95%CI) | P value | |
| Age (> 60 yr) | 0.676 (0.082-5.580) | 0.589 | 1.151 (0.278-4.768) | 0.846 |
| Sex (male) | 0.992 (0.193-5.104) | 0.992 | 1.488 (0.356-6.214) | 0.586 |
| Smoking | 0.392 (0.091-1.696) | 0.210 | 1.307 (0.316-5.408) | 0.712 |
| Alcohol | 0.501 (0.116-2.165) | 0.355 | 0.418 (0.101-1.726) | 0.228 |
| H. pylori infection | 1.294 (0.299-5.594) | 0.730 | 1.553 (0.376-6.421) | 0.543 |
- Citation: Kim JW, Jang JY, Chang YW, Kim YH. Clinical features of second primary cancers arising in early gastric cancer patients after endoscopic resection. World J Gastroenterol 2015; 21(27): 8358-8365
- URL: https://www.wjgnet.com/1007-9327/full/v21/i27/8358.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i27.8358