Copyright
©The Author(s) 2015.
World J Gastroenterol. Jul 21, 2015; 21(27): 8304-8313
Published online Jul 21, 2015. doi: 10.3748/wjg.v21.i27.8304
Published online Jul 21, 2015. doi: 10.3748/wjg.v21.i27.8304
Table 1 Effect of acupuncture on gastric and colonic motility
Organ | Subjects | Methods | Findings | Ref. |
Stomach | Normal mice | EA at ST-36 | ST-36-gastric motility ↑ | [48] |
EA at CV-12 | CV-12-gastric motility ↓ | |||
Rats with gastric mucosal damage | EA at acupoints in | Gastric motility ↑ | [22] | |
Foot-Yangming Meridian | ||||
Normal mice | EA at CV-12 | Gastric motility ↓ | [29] | |
Normal rats | EA at ST-36 | Gastric motility ↑ | [30] | |
Dogs with impaired gastric motility induced by RD | EA at ST-36 | Gastric motility ↑ | [18] | |
Healthy human | Manual acupuncture at | Normogastria ↓ | [32] | |
both PC-6 and ST-36 | Bradygastria ↑ | |||
Colon | Conscious dogs | Manual acupuncture at acupoints in large intestine meridian or ST-25, BL-25, GV-1 | Only GV-1-colonic motility ↓ | [37] |
Conscious rats | EA at ST-36 | Colonic motility ↑ | [50] | |
Rats with stress | EA at ST-36 | Colonic motility ↓ | [35] |
Table 2 Mechanisms of acupuncture on gastrointestinal motility
Function | Subjects | Stimulation | Result | Mechanism | Ref. | |
Method | Region | |||||
Gastric motility | Dogs with RD | EA | ST-36 | Increase | Vagal activity | [18] |
opioid pathway | ||||||
Healthy volunteers | MA | ST-36 | Increase | Vagal pathway | [21] | |
Rats | EA | Foot-Yangming Meridian | Increase | Brain-gut peptide | [22] | |
Wild-type mice | EA | CV-12 | Decrease | TRPV1 receptor | [29] | |
Rats | EA | ST-36 | Increase | NMDA receptors | [30] | |
Colonic motility | Rats | EA | ST-36 | Increase | Parasympathetic efferent pathway | [50] |
Rats | TENS | Hind limbs | Decrease | OXT expression | [54] |
Table 3 Clinical trials associated with acupuncture and gastrointestinal Regulation
Trial design | Subjects | Method | Acupoints | Result | Ref. |
Randomized controlled trial | Healthy persons administered with mosapride citrate | Manual acupuncture | LI-4 and PC-6 | GI motility ↓ | [32] |
Non-randomized controlled trial | Healthy persons administered with loperamide | Manual acupuncture | LI-4 and PC-6 | GI motility ↑ | [33] |
Non-randomized controlled trial | Healthy persons | Manual acupuncture | LI-4 and PC-6 | Intestinal motility - | [34] |
Randomized controlled trial | Healthy volunteers | Manual acupuncture | ST-36 | GI motility ↑ | [21] |
Randomized controlled trial | Healthy volunteers | Manual acupuncture | ST-36 and PC-6 | Normogastria↓ | [31] |
Bradygastria ↑ |
- Citation: Li H, He T, Xu Q, Li Z, Liu Y, Li F, Yang BF, Liu CZ. Acupuncture and regulation of gastrointestinal function. World J Gastroenterol 2015; 21(27): 8304-8313
- URL: https://www.wjgnet.com/1007-9327/full/v21/i27/8304.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i27.8304