Copyright
©The Author(s) 2015.
World J Gastroenterol. May 14, 2015; 21(18): 5560-5567
Published online May 14, 2015. doi: 10.3748/wjg.v21.i18.5560
Published online May 14, 2015. doi: 10.3748/wjg.v21.i18.5560
Table 1 Clinicopathological characteristics of the 74 patients (84 lesions) n (%)
Sex (male/female) | 54/21 |
Age, yr, median (range) | 64 (33-84) |
Location | |
1st portion | 12 (14) |
2nd portion | 68 (81) |
3rd portion | 4 (5) |
Final lesion diameter, mm, median (range) | 14.5 (2-80) |
Gross type | |
Is, Isp, Ip | 17 (20) |
IIa | 25 (30) |
IIa + Is, IIa + IIc, Is + IIc | 38 (45) |
IIc | 4 (5) |
Biopsy histology | |
Non-neoplastic | 2 (2) |
LGA | 19 (23) |
HGA | 7 (8) |
Carcinoma | 46 (55) |
NA | 10 (12) |
Treatment | |
Endoscopic resection | 35 (42) |
Surgical resection | 49 (58) |
Final histology | |
Hyperplasia | 3 (4) |
LGA | 10 (12) |
HGA | 5 (6) |
Carcinoma | 65 (77) |
NE | 1 (1) |
Table 2 Diagnoses of endoscopy, biopsy, and final histology after treatment n (%)
Final histology | |||||
Non-neoplastic | LGA | HGA | Carcinoma | ||
Endoscopic Dx (n = 83) | Non-neoplastic | 0 | 1 (50) | 0 | 1 (50) |
(n = 2) | |||||
Adenoma (n = 24) | 1 (4) | 8 (33) | 3 (13) | 12 (50) | |
Carcinoma (n = 57) | 2 (3.5) | 1 (2) | 2 (3.5) | 52 (91) | |
Biopsy Dx(n = 73) | Non-neoplastic | 0 | 2 (100) | 0 | 0 |
(n = 2) | |||||
LGA (n = 19) | 2 (11) | 5 (26) | 1 (5) | 11 (58) | |
HGA (n = 7) | 1 (14) | 0 | 1 (14) | 5 (71) | |
Carcinoma (n = 45) | 0 | 0 | 3 (7) | 42 (93) |
Table 3 Comparison of endoscopic and biopsy diagnoses with final histology
Final histology | |||
Non-carcinoma | Carcinoma | ||
Endoscopic Dx (n = 83) | Non-carcinoma (n = 26) | 12 | 14 |
Carcinoma (n = 57) | 5 | 52 | |
Sensitivity, 80%; Specificity, 72%; Accuracy, 78% | |||
Biopsy Dx (n = 73) | Non-carcinoma (n = 28) | 12 | 16 |
Carcinoma (n = 45) | 3 | 42 | |
Sensitivity, 72%; Specificity, 80%; Accuracy, 74% |
Table 4 Preoperative endoscopic factors associated with the final histology of adenoma or carcinoma
Factor | Adenoma (n = 15) | Carcinoma (n = 65) | P value1 | |
Location, n | 1st portion (n = 11) | 4 | 7 | NS |
2nd portion (n = 65) | 11 | 54 | ||
3rd portion (n = 4) | 0 | 4 | ||
Preoperative diameter, mm, n | < 20 (n = 53) | 13 | 40 | 0.060 |
≥ 20 (n = 27) | 2 | 25 | ||
Color, n | White or isocolor (n = 34) | 12 | 22 | 0.001 |
Red (n = 46) | 3 | 43 | ||
Depressed area, n | Present (n = 40) | 3 | 37 | 0.009 |
Absent (n = 40) | 12 | 28 | ||
Lobulation, n | Present (n = 42) | 9 | 33 | 0.500 |
Absent (n = 38) | 6 | 32 | ||
Marginal whitening, n | Present (n = 52) | 9 | 43 | NS |
Absent (n = 28) | 6 | 22 | ||
Gross type, n | Elevated type | 13 | 26 | 0.002 |
(Is, Isp, Ip, IIa) (n = 39) | ||||
Depressed type (IIc) (n = 4) | 0 | 4 | ||
Mixed type (IIa + Is, IIa + IIc, Is + IIc) (n = 37) | 2 | 35 |
Table 5 Multivariate logistic regression analysis of endoscopic factors indicative of duodenal carcinoma
Factor | OR | P value | 95%CI |
Color | 2.360 | 0.038 | 1.04-5.32 |
Lobulation | 0.553 | 0.389 | 0.14-2.13 |
Marginal whitening | 0.546 | 0.359 | 0.15-1.98 |
Gross type | 2.258 | 0.064 | 0.95-5.35 |
- Citation: Kakushima N, Kanemoto H, Sasaki K, Kawata N, Tanaka M, Takizawa K, Imai K, Hotta K, Matsubayashi H, Ono H. Endoscopic and biopsy diagnoses of superficial, nonampullary, duodenal adenocarcinomas. World J Gastroenterol 2015; 21(18): 5560-5567
- URL: https://www.wjgnet.com/1007-9327/full/v21/i18/5560.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i18.5560