Improved specimen adequacy using jumbo biopsy forceps in patients with Barrett's esophagus

Table 1 Principal results of the study n (%)

Variable	Total(n = 436)	Forceps type
		Large-capacity			Jumbo(n = 92)
		A(n = 121)	B(n = 115)	C(n = 108)
Adequate specimen	136 (31)	32 (26)	20 (17)	19 (18)	65 (71)bdf
Median size, mm	2	2	1.6	2a	2.4bdf
Muscularis mucosa present	205 (47)	54 (45)a	26 (23)	51 (47)a	74 (80)bdf
Good orientation	269 (62)	74 (61)h	51 (44)	73 (66)h	71 (77)d

^bP < 0.001 vs A;

^dP < 0.001 vs B;

^fP < 0.001 vs C;

^aP < 0.005 vs B;

^hP < 0.01 vs B.

Table 2 Detection of intestinal metaplasia and intraepithelial neoplasia n (%)

Variable	Total(n = 436)	Forceps type
		Large-capacity			Jumbo(n = 92)
		A(n = 121)	B(n = 115)	C(n = 108)
Intestinal metaplasia	386 (89)	103 (85)	99 (86)	98 (91)	86 (93)
No IEN	332 (76)	97 (80)	90 (78)	79 (73)	66 (72)
Low-grade IEN	91 (21)	22 (18)	22 (19)	26 (24)	21 (23)
High-grade IEN	13 (3)	2 (2)	3 (3)	3 (3)	5 (5)
Diagnostic yield (per biopsy)	0.24	0.20	0.22	0.27	0.28

IEN: Intraepithelial neoplasia.