Copyright
©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 7, 2015; 21(17): 5328-5335
Published online May 7, 2015. doi: 10.3748/wjg.v21.i17.5328
Published online May 7, 2015. doi: 10.3748/wjg.v21.i17.5328
Improved specimen adequacy using jumbo biopsy forceps in patients with Barrett's esophagus
Jan Martinek, Zuzana Vackova, Jana Krajciova, Julius Spicak, Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, 14021 Prague, Czech Republic
Jan Martinek, Faculty of Medicine, University of Ostrava, 70103 Ostrava, Czech Republic
Jana Maluskova, Marek Kollar, Department of Pathology, IKEM, 14021 Prague, Czech Republic
Magdalena Stefanova, Department of Internal Medicine, Hospital “Na Frantisku”, 11000 Prague, Czech Republic
Inna Tuckova, Department of Pathology, Central Military Hospital, 16902 Prague, Czech Republic
Stepan Suchanek, Miroslav Zavoral, Department of Medicine, Charles University, Military University Hospital, 16902 Prague, Czech Republic
Author contributions: Martinek J, Vackova Z, Zavoral M and Spicak J designed the research; Martinek J and Stefanova M performed endoscopic examinations; Martinek J, Suchanek S and Krajciova J performed statistical analyses; Vackova Z and Kollar M collected and analyzed data; Maluskova J and Tuckova I assessed biopsy specimens; Martinek J, Suchanek S, Vackova Z, Kollar M and Spicak J wrote the paper.
Supported by Czech Health Ministry, No. IGA NT/13636.
Ethics approval: The study was reviewed and approved by the Institutional Review Board of Institute for Clinical and Experimental Medicine in Prague and by the Institutional Review Board of University Military Hospital in Prague.
Clinical trial registration: The study is registered at Czech Ministry of Health. The registration number is NT/13636.
Informed consent: All study participants provided informed written consent prior to study enrollment.
Conflict-of-interest: The authors have no conflicts of interest to declare.
Data sharing: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Jan Martinek, MD, PhD, AGAF, Associate Professor, Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Vídeňska 1921, 14021 Prague, Czech Republic. jan.martinek@volny.cz
Telephone: +420-26-1362617 Fax: +42-26-1362615
Received: November 17, 2014
Peer-review started: November 17, 2014
First decision: December 11, 2014
Revised: January 21, 2015
Accepted: February 11, 2015
Article in press: February 11, 2015
Published online: May 7, 2015
Processing time: 177 Days and 9.2 Hours
Peer-review started: November 17, 2014
First decision: December 11, 2014
Revised: January 21, 2015
Accepted: February 11, 2015
Article in press: February 11, 2015
Published online: May 7, 2015
Processing time: 177 Days and 9.2 Hours
Core Tip
Core tip: Good quality biopsy specimens are required for reliable diagnosis of early neoplasia in patients with Barrett’s esophagus. It remains controversial whether the use of jumbo forceps provides an advantage over large-capacity forceps. We compared the sampling quality using four different biopsy forceps. Biopsies were obtained using a diagnostic endoscope during a single endoscopy. We found a significantly higher proportion of adequate biopsy samples with jumbo forceps as compared to the three large capacity forceps. Thus, jumbo biopsy forceps, when used with a diagnostic endoscope, provide more adequate specimen as compared to large-capacity forceps.