Appropriate empirical antibiotic use and 30-d mortality in cirrhotic patients with bacteremia

Table 1 Isolated bacteria n (%)

	n = 102
Gram (+)
Staphylococcus aureus	13 (13)
Coagulase negative staphylococci	21 (21)
Streptococcus species	7 (7)
Enterococcus species	8 (8)
1Other Gram (+) pathogens	3 (3)
Gram (-)
Escherichia coli	16 (16)
Klebsiella pneumoniae	18 (18)
Pseudomonas aeruginosa	3 (3)
Acinetobacter baumannii	5 (5)
2Other Gram (-) pathogens	8 (8)

¹Other Gram (+) pathogens were Micrococcus luteus (n = 2), and Leuconostoc (n = 1);

²Other Gram (-) pathogens were Aeromonas (n = 3), Citrobacter (n = 1), Flavobacterium (n = 1), Morganella (n = 1), Serratia (n = 1), Vibrio vulnificus (n = 1).

Table 2 Factors associated with 30-d mortality

Factors	Univariate	P value	Multivariate	P value
Age (per years)	1.00 (0.97-1.03)	0.89
Male ( vs female)	0.92 (0.42-2.1)	0.84
Child-Pugh class (C vs A/B)	7.93 (2.40-26.1)	0.01	7.18 (2.07-24.91)	0.002
Multiresistant pathogen	1.49 (0.73-3.06)	0.26
Inappropriate antibiotic use	2.00 (0.97-4.13)	0.06	3.24 (1.50-7.00)	0.003
Gastrointestinal bleeding	2.12 (1.01-4.43)	0.05	2.92 (1.33-6.38)	0.007
Infection type (community vs non-community)	0.76 (0.35-1.64)	0.49
Systemic inflammatory response syndrome	1.79 (0.77-4.16)	0.17
Septic shock	4.26 (2.10-8.66)	< 0.01	3.39 (1.56-7.37)	0.002