Electrocardiograms changes in children with functional gastrointestinal disorders on low dose amitriptyline

Table 1 Effect of amitriptyline and placebo on cardiac conduction in children

	HR (beats/min)		PR (ms)		QRS (ms)		QTc (ms)
Parameters	Pre EKG	Post EKG	Pre EKG	Post EKG	Pre EKG	Post EKG	Pre EKG	Post EKG
Drug
mean ± SD	75.92 ± 9.44	85.2 ± 17.4	135 ± 12.97	134.5 ± 11.25	83.67 ± 6.81	85.33 ± 7.15	406.91 ± 12.6	418 ± 13.8
2 tailed t test P value	0.024a		0.8429		0.2098		0.0107a
Correlation coefficient - r	0.7367		0.7608		0.8084		0.4923
Placebo
mean ± SD	69.22 ± 12.26	74.05 ± 10.06	132.6 ± 16.35	137.5 ± 21.53	86.7 ± 8.95	83.8 ± 8.98	415.5 ± 16.82	422.6 ± 18.53
n	18	18	18	18	18	18	18	18
2 tailed t test P value	0.0783		0.1394		0.0937		0.0498a
Correlation coefficient - r	0.5343		0.7841		0.7037		0.6773

^aP < 0.05, placebo group vs control group.