Ileal pouch anal anastomosis with modified double-stapled mucosectomy-the experience in China

Table 1 Demographic and perioperative data

Age at operation (yr) (mean ± SD)	42.4 ± 12.5
Gender (male:female)	22:23
Diagnosis (UC:FAP)	29:16:00
Median hemoglobin at the time of admission, g/L [median (range)]	85 (38-148)
Operative time, min [median (range)]	225 (195-325)
Median volume of blood transfusion, mL [median (range)]	600 (0-1600)
Days to regular diet, d [median (range)]	6 (4-14)
Length of postoperative hospitalization, d [median (range)]	12 (9-35)
Interval to closure of the ileostomy, mo [median (range)]	5 (4-12)

UC: Ulcerative colitis; FAP: Familial adenomatous polyposis.

Table 2 Stool frequency, urgency, pad usage, diet, medication in patients underwent ileal pouch-anal anastomosis at 1 year, 2.5 years and 5 years after closure of stoma n (%)

	Score	1 yr (n = 45)	2.5 yr (n = 35)	5 yr (n = 24)	P value3
24-h stool frequency					0.014
< 5	0	10 (22.2)	19 (54.2)	14 (58.3)
5-8	1	31 (68.8)	14 (40.0)	8 (33.3)
> 8	2	4 (8.8)	2 (5.7)	2 (8.3)
Night time defecation					0.001
Never	0	2 (4.4)	7 (20.0)	6 (25)
Weekly	1	15 (33.3)	20 (57.1)	13 (54.2)
Every night	2	28 (62.2)	8 (22.8)	5 (20.8)
Urgency of defecation1					0.382
> 30 min	0	25 (55.5)	25 (71.4)	17 (70.8)
10-30 min	1	16 (35.5)	8 (22.9)	7 (29.1)
< 10 min	2	4 (8.8)	2 (5.7)	0 (0)
Use of pad daytime	1	6 (13.3)	2 (5.7)	1 (4.2)	0.326
Use of pad at night	1	6 (13.3)	3 (8.6)	1 (4.2)	0.454
Soiling or seepage during daytime	1	8 (17.7)	2 (5.7)	2 (8.3)	0.210
Soiling or seepage at night	1	15 (33.3)	7 (20)	5 (20.8)	0.026
Peri-anal soreness					0.989
No	0	38 (84.4)	30 (85.7)	21 (87.5)
Occasional	1	5 (11.1)	4 (11.4)	2 (8.3)
Permanent	2	2 (4.4)	1 (2.9)	1 (4.2)
Dietary restrictions	1	23 (51.1)	8 (22.8)	2 (8.3)	0.001
Regular medication for stool regulation	1	20 (44.4)	6 (17.1)	1 (4.2)	0.000
Social handicap2	1	4 (8.8)	2 (5.7)	2 (8.3)	0.862
Functional Oresland score [median (range)]	15	6 (1-12)	3 (0-11)	2 (0-9)

¹Urgency of defecation is inability to defer evacuation for more than 30 min;

²Social handicap is not able to resume full time occupation or to participate in social life;

³χ² test of 45 patients.

Table 3 Kirwan classification after surgery n (%)

Kirwan classification	1 yr (n = 45)	2.5 yr (n = 35)	5 yr (n = 24)	P value1
Stage I (full continence)	30 (66.7)	28 (80)	19 (79.1)	0.785
Stage II (incontinence of gas)	5 (11.1)	3 (8.6)	2 (8.3)
Stage III (occasional minor soiling)	9 (20)	4 (11.4)	3 (12.5)
Stage IV (frequent major soiling)	1 (2.2)	0 (0)	0 (0)
Stage V (incontinence)	0 (0)	0 (0)	0 (0)

¹χ² test of 45 patients.