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World J Gastroenterol. Feb 21, 2013; 19(7): 1068-1078
Published online Feb 21, 2013. doi: 10.3748/wjg.v19.i7.1068
Published online Feb 21, 2013. doi: 10.3748/wjg.v19.i7.1068
Table 1 Effect of long interspersed nuclear element ORF-1 protein on the cytotoxic activity of chemotherapeutic drugs in vitro
| Drugs | IC50 (nmol/L) | |||
| FLAG | FLAG-ORF-1p | Control | siRNA | |
| Epirubicin | 36.04 ± 4.48 | 59.11 ± 3.37 | 28.06 ± 5.31 | 3.84 ± 0.48 |
| Cisplatin | 37.94 ± 2.90 | 119.32 ± 21.99 | 32.04 ± 3.71 | 2.89 ± 0.44 |
| Paclitaxel | 27.01 ± 3.91 | 29.01 ± 2.95 | 35.90 ± 7.03 | 7.36 ± 0.69 |
- Citation: Feng F, Lu YY, Zhang F, Gao XD, Zhang CF, Meredith A, Xu ZX, Yang YT, Chang XJ, Wang H, Qu JH, Zeng Z, Yang JL, Wang CP, Zhu YF, Cui JJ, Yang YP. Long interspersed nuclear element ORF-1 protein promotes proliferation and resistance to chemotherapy in hepatocellular carcinoma. World J Gastroenterol 2013; 19(7): 1068-1078
- URL: https://www.wjgnet.com/1007-9327/full/v19/i7/1068.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i7.1068