Brief Article
Copyright ©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Nov 21, 2013; 19(43): 7795-7803
Published online Nov 21, 2013. doi: 10.3748/wjg.v19.i43.7795
Table 1 Expression of annexin A1 protein in normal gastric epithelial cells and gastric adenocarcinoma cells
GroupnAnnexin A1 expression
NGEC150.49 ± 0.082
GAC151.06 ± 0.068b
Table 2 Annexin A1 expression in normal gastric mucosa and gastric carcinoma by immunohistochemistry n (%)
Tissue typenAnnexin A1 cases
WP value
-++ ++ + +
NGEC7537 (49.3)25 (33.3)13 (17.3)0 (0)45990
GAC7523 (30.7)11 (14.7)26 (34.7)15 (20.0)
Table 3 Relationship between annexin A1 protein expression and clinicopathological parameters of gastric carcinoma n (%)
ParametesnANXA1 cases
WilcoxonP value
-++ ++ + +
Sex1039.50.290
Male5015 (30.0)7 (14.0)17 (34.0)11 (22.0)
Female258 (32.0)4 (16.0)9 (36.0)4 (16.0)
Age (yr)840.00.394
≤ 60247 (29.2)5 (20.8)10 (41.7)2 (8.3)
> 605116 (31.4)6 (11.7)16 (31.4)13 (25.5)
Histological differentiation1350.00.520
High3410 (29.4)4 (11.8)12 (35.3)8 (23.5)
Moderate/poor4113 (31.7)7 (17.1)14 (34.1)7 (17.1)
Invasive depth514.50.008
T1-21910 (52.6)4 (21.1)3 (15.8)2 (10.5)
T3-45613 (23.2)7 (12.5)23 (41.1)13 (23.2)
N stage929.00.017
N03012 (40.0)6 (20.0)10 (33.3)2 (6.7)
N1-34511 (24.4)5 (11.1)16 (35.6)13 (28.9)
M stage348.50.017
M06923 (33.3)10 (14.5)25 (36.2)11 (15.9)
M160 (0)1 (16.7)1 (16.7)4 (66.7)
TNM stage1014.50.000
I-II3720 (54.1)4 (10.8)11 (29.7)2 (5.4)
III-IV383 (2.6)7 (10.5)15 (42.1)13 (44.7)
Tumor size1403.00.9735
≤ 5 cm3811 (28.9)6 (15.8)14 (36.8)7 (18.4)
< 5 cm3712 (32.4)5 (13.5)12 (32.4)8 (21.6)