Quantification of pancreatic exocrine function of chronic pancreatitis with secretin-enhanced MRCP

Table 1 Results in normal and chronic pancreatitis

	n	FE-1 (μg/g)	PFR (mL/min)	PT (min)
Normal	17	525.41 ± 94.44	8.18 ± 1.11	5.76 ± 1.71
Mild	14	464.95 ± 136.13	7.27 ± 2.04	7.71 ± 2.55
Moderate	19	301.55 ± 181.55	4.98 ± 2.57	9.10 ± 3.00
Advanced	3	229.30 ± 146.60	4.13 ± 1.83	12.33 ± 1.15
F value		9.45	9.59	9.06
P value		0.000	0.000	0.000

FE-1: Fecal elastase-1; PFR: Pancreatic flow output rate; PT: Peak time.

Table 2 Results in normal and reduced duodenal filling

	n	FE-1 (μg/g)	PFR (mL/min)	PT (min)
Normal DF ( grade 3)	40	453.64 ± 162.74	7.16 ± 2.34	7.28 ± 2.56
Reduced DF ( grade 1, 2)	13	285.59 ± 158.03	4.71 ± 1.92	9.61 ± 3.57
P value		0.002	0.001	0.012

FE-1: Fecal elastase-1; PFR: Pancreatic flow output rate; PT: Peak time; DF: Duodenal filling.

Table 3 Quantification of secretin enhanced magnetic resonance cholangiopancreatography vs Fecal elastase-1 n (%)

	Normal FE-1	Abnormal FE-1
Normal MRCPQ	18 (51.4)	3 (8.6)
Abnormal MRCPQ	4 (11.4)	10 (28.6)

MRCPQ (quantification of secretin enhanced magnetic resonance cholangiopancreatography) < 5 mL/min and FE-1 < 200 μg/g are abnormal K = 0.6. FE-1: Fecal elastase-1.

Table 4 Results of correlation

	M-ANNHEIM		DF
	r value	P value	r value	P value
PFR	0.55	0.000	0.36	0.009
FE-1	0.57	0.000	0.29	0.038

Correlation is significant at the 0.01 level (2-tailed). DF: duodenal filling.