Can eradication rate of gastric Helicobacter pylori be improved by killing oral Helicobacter pylori?

Table 1 Characteristics of the 431 patients

Diseases	Total	Male	Female	Age range (yr)	Mean age (yr)
Peptic ulcer	54	40	14	20-80	51.1
Chronic atrophic gastritis	48	32	16	46-82	58.5
Duodenitis	58	31	27	26-77	51.0
Superficial gastritis	231	95	136	18-74	49.6
Control group	40	17	23	18-67	44.0

Table 2 Results of Helicobacter pylori antigen test and ¹³C-urea breath test testing n (%)

HPS	13C-UBT
	Positive	Negative
Peptic ulcer (n = 54)
Positive	29 (53.7)	8 (14.8)
Negative	14 (25.9)	3 ( 5.6)
Chronic atrophic gastritis (n = 48)
Positive	24 (50.0)	14 (29.1)
Negative	8 (16.7)	2 ( 4.2)
Duodenitis (n = 58)
Positive	35 (60.3)	16 (27.6)
Negative	2 ( 3.4)	5 (8.7)
Superficial gastritis (n = 231)
Positive	79 (34.2)	89 (38.5)
Negative	25 (10.8)	38 (16.5)
Control group (n = 40)
Positive	12 (30.0)	21 (52.5)
Negative	5 (12.5)	2 ( 5.0)

HPS: Helicobacter pylori antigen test; ¹³C-UBT: ¹³C-urea breath test.

Table 3 Eradication rate of gastric Helicobacter pylori and prevalence of oral Helicobacter pylori after treatment in all groups n (%)

Group	Eradication rate of gastric Helicobacter pylori	Prevalence of oral Helicobacter pylori
O-G+t	42 (93.3)ac	0 (0.0)a
O+G+t	40 (78.4)	39 (76.5)
O+G+tm	54 (90.0)b	32 (53.3)a
O+G+tmp	54 (94.7)abc	29 (50.9)a

^aP < 0.05 vs O+G+t group;

^bP > 0.05 vs O-G+t group;

^cP > 0.05 vs O+G+tm group.

Table 4 Eradication rate of gastric Helicobacter pylori after treatment in all gastric disease groups n (%)

Group	Gastric diseases
	Peptic ulcer	Chronic atrophic gastritis	Duodenitis	Superficial gastritis	Control group
O-G+t	10 (100.0)	6 (100.0)	2 (100.0)	19 (86.4)	5 (100.0)
O+G+t	9 (90.0)	7 (87.5)	8 (72.7)	12 (70.6)	4 (80.0)
O+G+tm	9 (100.0)	10 (100.0)	9 (75.0)	22 (88.0)	4 (100.0)
O+G+tmp	9 (100.0)	5 (100.0)	10 (91.0)	27 (93.1)	3 (100.0)