Colonic diverticulitis with comorbid diseases may require elective colectomy

Table 1 Characteristics of patients with colonic diverticulitis n (%)

	Surgery group (n = 19)	Non-surgery group (n = 227)	P value
Age (yr)	66.21 ± 15.77	69.81 ± 12.36	0.344
Sex			0.670
Male	12 (36.6)	132 (58.1)
Female	7 (63.2)	95 (41.9)
Smoking			0.005
Yes	6 (31.6)	23 (10.1)
No	13 (68.4)	204 (89.9)
Albumin			< 0.001
< 3	11 (57.9)	21 (9.3)
≥ 3	8 (42.1)	206 (90.7)
Aspirin			0.017
Yes	7 (36.8)	35 (15.4)
No	12 (63.2)	192 (84.6)
NSAIDs			< 0.001
Yes	7 (36.8)	13 (5.7)
No	12 (63.2)	214 (94.3)
Steroids			0.138
Yes	2 (10.5)	8 (3.5)
No	17 (89.5)	219 (96.5)
Cardiovascular disease			0.014
Yes	8 (42.1)	42 (18.5)
No	11 (57.9)	185 (81.5)
DM			0.014
Yes	7 (36.8)	34 (15.0)
No	12 (63.2)	193 (85.0)
Liver disease			0.862
Yes	1 (5.3)	10 (4.4)
No	18 (94.7)	217 (95.6)
Uremia			0.997
Yes	1 (5.3)	12 (5.3)
No	18 (94.7)	215 (94.7)
Gout			< 0.001
Yes	5 (26.3)	8 (3.5)
No	14 (73.7)	219 (96.5)
Pulmonary disease			0.658
Yes	2 (10.5)	18 (7.9)
No	17 (89.5)	209 (92.1)
Peptic ulcer disease			0.694
Yes	2 (10.5)	21 (9.3)
No	17 (89.5)	206 (90.7)

DM: Diabetes mellitus; NSAID: Non-steroidal anti-inflammatory drug.

Table 2 Characteristics of mortality case

Case	Age (yr)	Sex	Risk factors
Surgery
1	75	Male	Gout, low albumin level, NSAIDs
2	60	Male	Uremia, DM
3	77	Female	Pulmonary disease, low albumin level
Non-surgery
1	81	Male	DM, uremia
2	79	Male	NSAIDs, low albumin level,uremia
3	68	Male	Pulmonary disease, DM
4	74	Female	Pulmonary disease, uremia

DM: Diabetes mellitus; NSAID: Non-steroidal anti-inflammatory drug.

Table 3 Surgical complication of urgent surgery n (%)

Complications	n = 19
Wound infection	10 (52.6)
Wound infection needing debridement	4 (21.0)
Pneumonia complicated with acute respiratory distress syndrome	2 (10.5)
Urinary tract infection	1 (5.2)
Mortality	3 (15.7)

Table 4 Risk factors for urgent colectomy for colonic diverticulitis according to univariate analysis

Variables	B	SE	OR (95%CI)	P value
Smoking	1.409	0.540	4.094 (1.420-11.805)	0.009
Albumin	2.602	0.518	13.488 (4.886-37.232)	< 0.001
Aspirin	1.163	0.510	3.200 (1.178-8.693)	0.023
NSAIDs	2.262	0.555	9.603 (3.237-28.485)	< 0.001
CV disease	1.164	0.495	3.203 (1.214-8.454)	0.019
DM	1.197	0.511	3.311 (1.217-9.009)	0.019
Gout	2.280	0.633	9.777 (2.826-33.823)	< 0.001

DM: Diabetes mellitus; NSAID: Non-steroidal anti-inflammatory drug; CV: Cardiovascular.

Table 5 Risk factors for urgent colectomy for colonic diverticulitis according to multivariable analysis

Variables	B	SE	OR (95%CI)	P value
Age	-0.046	0.662	0.955 (0.261-3.497)	0.944
Sex	0.001	0.025	1.001 (0.953-1.050)	0.983
Smoking	2.169	0.873	8.747 (1.580-48.405)	0.013
Albumin	3.467	0.806	32.049 (6.599-155.644)	< 0.001
Aspirin	-0.873	1.382	0.418 (0.028-6.270)	0.527
NSAIDs	3.323	1.212	27.745 (2.578-298.594)	0.006
Steroids	0.785	1.313	2.193 (0.167-28.780)	0.550
CV disease	1.320	1.262	3.745 (0.316-44.390)	0.295
DM	1.810	0.726	6.109 (1.473-25.333)	0.013
Liver disease	-0.291	1.373	0.748 (0.051-11.028)	0.832
Uremia	0.898	1.250	2.454 (0.212-28.416)	0.473
Gout	0.470	1.335	1.600 (0.117-21.911)	0.725

DM: Diabetes mellitus; NSAID: Non-steroidal anti-inflammatory drug; CV: Cardiovascular.