Proton pump inhibitor resistance, the real challenge in gastro-esophageal reflux disease

doi:10.3748/wjg.v19.i39.6529

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 19, Issue 39

This Article

Academic Content and Language Evaluation of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (7029)

All Articles published online

The chart showing PDF series, HTML series, Tables (1-1) series.

Item

Count

PDF

592

HTML

4423

Tables (1-1)

227

Sum=5242

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

859

Download

928

Sum=1787

Oct 21, 2013 (publication date) through Nov 19, 2024

Times Cited of This Article

Times Cited (61)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Topic Highlight

World J Gastroenterol. Oct 21, 2013; 19(39): 6529-6535
Published online Oct 21, 2013. doi: 10.3748/wjg.v19.i39.6529

Table 1 Principal mechanisms and factors involved in proton pump inhibitor resistance

Adherence to PPI therapy

Compliance

Dosing, time

Reflux pattern

Weakly acidic reflux

Proximal reflux

Mixed reflux

Residual acid refluxes

Esophageal hypersensitivity

Other mechanisms

Reduced PPI bioavailability

Increased PPI metabolism

Mutations cyt. p450

PPI: Proton pump inhibitor.

Citation: Cicala M, Emerenziani S, Guarino MPL, Ribolsi M. Proton pump inhibitor resistance, the real challenge in gastro-esophageal reflux disease. World J Gastroenterol 2013; 19(39): 6529-6535
URL: https://www.wjgnet.com/1007-9327/full/v19/i39/6529.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i39.6529