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World J Gastroenterol. Sep 28, 2013; 19(36): 6035-6043
Published online Sep 28, 2013. doi: 10.3748/wjg.v19.i36.6035
Published online Sep 28, 2013. doi: 10.3748/wjg.v19.i36.6035
Table 1 Characteristics of patients with Roux-en-Y gastric bypass and laparoscopic adjustable gastric band n (%)
RYGB (n = 609) | LAGB (n = 686) | |
Gender (M:F) | 116: 493 | 131: 555 |
Age (yr) | 42.4 ± 10.5b | 37.2 ± 9.4 |
Initial BMI (kg/m2) | 46.8 ± 7.1b | 40.4 ± 4.2 |
Co-morbidities (sub-group analysis) | (n = 301) | (n = 545) |
Total co-morbidities | 216 (71.0) | 363 (66.6) |
Type 2 diabetes mellitus (n) | 82 | 95 |
Hypertension (n) | 51 | 157 |
Hyperlipidemia (n) | 116 | 117 |
Obstructive sleep apnoea (n) | 97b | 113 |
Duration of follow-Median (yr) | 2.0 (1.0-5.0) | 1.6 (1.0-2.2) |
Table 2 Acute- and long-term complications between Roux-en-Y gastric bypass and laparoscopic adjustable gastric band
RYGB (n= 609) | LAGB (n= 686) |
Acute complications (n) | |
n = 49 (8.0%) | n = 3 (0.5%) (P < 0.0001 vs RYGB) |
Wound infection (35) | Small leak, required band removal after 1 d (1) |
Abdominal sepsis (3) | Post-op respiratory infection (1) |
Splenic trauma (2) | Large wound haematoma, drained spontaneously (1) |
DVT and PE (2) | |
Endoscopy for stomal obstruction (4) | |
Mechanical failure (3) | |
Long-term complications (n) | |
n = 13 (2.1%) | n = 61 (8.9%) (P < 0.0001 vs RYGB) |
Reversal of RYGB (n = 1) | Removed and replaced LB (19) |
Incisional hernia (n = 7) | Replacement of port (16) |
Bowel obstruction (n = 5) | Removed LB (13) |
Converted to RYGB (7) | |
Stomal obstruction required dilation (3) | |
Mechanical failure (3) |
Table 3 Characteristics of patients with and without biochemical data
RYGB (n = 609) | LAGB (n = 686) | |||||
Biochemical data (n = 301) | No biochemical data (n = 308) | P-value | Biochemical data (n = 545) | No biochemical data (n = 141) | P-value | |
Gender (M:F) | 63:238 | 53:255 | > 0.05 | 101:444 | 30:111 | > 0.05 |
Age (yr) | 42.9 ± 10.2 | 42.0 ± 10.6 | > 0.05 | 37.8 ± 9.4 | 37.1 ± 9.5 | > 0.05 |
Initial BMI (kg/m2) | 45.9 ± 7.5 | 47.0 ± 7.4 | > 0.05 | 40.6 ± 4.1 | 40.3 ± 4.2 | > 0.05 |
BMI reduction at 12 mo (kg/m2) | -6.5 ± 3.4 | -7.7 ± 4.6 | > 0.05 | -1.2 ± 0.8 | -1.4 ± 0.9 | > 0.05 |
BMI reduction at 3 yr (kg/m2) | -18.2 ± 3.9 | -19.0 ± 4.9 | > 0.05 | -4.9 ± 2.6 | 4.3 ± 2.4 | > 0.05 |
Table 4 Co-morbidities before and 12 mo after Roux-en-Y gastric bypass and laparoscopic adjustable gastric band n (%)
RYGB | LAGB | P-value | |
(n = 301) | (n = 554) | (RYGB vs LAGB) | |
Diabetes mellitus | |||
Pre-operative | 83 (28) | 127 (23) | 0.34 |
Normalization of fasting blood glucose1 | 26 (33) | 22 (17) | 0.02 |
Hyper-cholesterolemia | |||
Pre-operative | 125 (42) | 224 (41) | 0.77 |
Normalization of total plasma cholesterol1 | 65 (52) | 9 (4) | < 0.001 |
Hyper-triglyceridemia | |||
Pre-operative | 63 (21) | 124 (22) | 0.86 |
Normalization of plasma triglyceride1 | 51 (81) | 34 (27) | < 0.0001 |
Obstructive sleep apnoea | |||
Pre-operative | 100 (33) | 130 (23) | 0.02 |
No longer required CPAP at 12 mo | 10 (10) | 4 (3) | 0.04 |
Table 5 Fasting blood glucose and lipid profile after Roux-en-Y gastric bypass and laparoscopic adjustable gastric band
RYGB | LAGB | P-value | |
(n = 301) | (n = 554) | (RYGB vs LAGB) | |
Fasting blood sugar | |||
Prior to surgery | 5.9 ± 1.6 | 5.7 ± 1.7 | 0.12 |
6-month post-op | 5.3 ± 1.6b | 5.5 ± 1.9b | 0.57 |
12-month post-op | 5.0 ± 1.7b | 5.4 ± 1.6b | 0.02 |
Total cholesterol | |||
Prior to surgery | 5.2 ± 1.0 | 5.2 ± 1.0 | 0.65 |
6-month post-op | 4.2 ± 0.9b | 5.2 ± 1.0 | < 0.0001 |
12-month post-op | 4.3 ± 0.9b | 5.0 ± 1.0b | < 0.0001 |
Total triglyceride | |||
Prior to surgery | 1.7 ± 0.5 | 2.0 ± 0.6 | 0.44 |
6-month post-op | 1.2 ± 0.6b | 1.5 ± 0.6 | 0.01 |
12-month post-op | 1.1+0.4b | 1.5 ± 0.5 | 0.04 |
HDL | |||
Prior to surgery | 1.3 ± 0.3 | 1.3 ± 0.3 | 0.26 |
6-month post-op | 1.3 ± 0.3 | 1.4 ± 0.3b | 0.21 |
12-month post-op | 1.4 ± 0.3b | 1.5 ± 0.3b | 0.56 |
- Citation: Nguyen NQ, Game P, Bessell J, Debreceni TL, Neo M, Burgstad CM, Taylor P, Wittert GA. Outcomes of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding. World J Gastroenterol 2013; 19(36): 6035-6043
- URL: https://www.wjgnet.com/1007-9327/full/v19/i36/6035.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i36.6035