Liao XH, Cao X, Liu J, Xie XH, Sun YH, Zhong BH. Prevalence and features of fatty liver detected by physical examination in Guangzhou. World J Gastroenterol 2013; 19(32): 5334-5339 [PMID: 23983438 DOI: 10.3748/wjg.v19.i32.5334]
Corresponding Author of This Article
Bi-Hui Zhong, MD, Professor, Department of Gastroenterology, Huangpu Division of the First Affiliated Hospital, Sun Yat-sen University, No. 183 Huangpu East Road, Guangzhou 510700, Guangdong Province, China. sophiazhong@hotmail.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Brief Article
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Aug 28, 2013; 19(32): 5334-5339 Published online Aug 28, 2013. doi: 10.3748/wjg.v19.i32.5334
Table 1 Prevalence of dysmetabolic diseases and biochemical abnormalities in the total study population n (%)
Patients examined
Positive patients
Hyperlipidemia
2715
1035 (38.1)
Fatty liver
2605
677 (26.0)
Increased ALT and/or AST levels
3393
405 (11.9)
Gallstone
2605
296 (11.4)
HBsAg
2244
198 (8.8)
Hyperglycemia
2767
203 (7.3)
Hypertension
2938
210 (7.3)
Hyperuricemia
2700
167 (6.2)
Increased Scr levels
2150
10 (6.2)
Table 2 Age and sex distribution of overall fatty liver prevalence
Age (yr)
All patients
Patients with fatty liver
Overall prevalence
Prevalence in males
Prevalence in females
χ2
P value
18-19
17
1
5.80%
7.10%
0.00%
-
-
20-29
1055
55
5.20%
6.40%
2.30%
7.47
0.006
30-39
1003
206
20.50%
26.70%
8.70%
44.80
< 0.001
40-49
799
212
26.50%
34.50%
16.80%
31.78
< 0.001
50-59
331
123
37.20%
35.90%
39.00%
0.32
0.569
60-69
147
58
39.50%
37.80%
42.10%
0.27
0.601
≥ 70
81
22
27.10%
24.50%
32.10%
0.54
0.464
Total
2605
677
26.00%
32.50%
15.30%
95.18
< 0.001
Table 3 Prevalence of dysmetabolic diseases and biochemical abnormalities in the 677 patients diagnosed with fatty liver n (%)
Patients examined
Positive patients
Increased ALT and/or AST levels
676
199 (29.4)
Hypertriglyceridemia
635
197 (31.0)
Mixed type hyperlipidemia
635
135 (21.3)
Hypercholesterolemia
635
92 (14.5)
Hyperglycemia
640
116 (18.1)
Hypertension
636
102 (16.0)
Gallstone
677
97 (14.4)
Hyperuricemia
627
87 (13.9)
HBsAg
506
39 (7.7)
Increased Scr levels
507
3 (0.6)
Table 4 Sex distribution of prevalence of dysmetabolic diseases and biochemical abnormalities in the 430 subjects with fatty liver n (%)
All patients
Male patients
Female patients
χ2
P value
Increased ALT and/or AST levels
129 (30.0)
113 (32.6)
16 (19.3)
5.63
0.018
Hypertriglyceridemia
135 (31.4)
125 (36.0)
10 (12.0)
17.87
< 0.001
Mixed type hyperlipidemia
90 (20.9)
65 (18.7)
25 (30.1)
5.25
0.022
Hypercholesterolemia
53 (12.3)
33 (9.5)
20 (24.1)
13.19
< 0.001
Hyperglycemia
76 (17.6)
59 (17.0)
17 (20.5)
0.56
0.455
Hypertension
69 (16.0)
53 (15.3)
16 (19.3)
0.80
0.372
Hyperuricemia
66 (15.3)
60 (17.3)
6 (7.2)
5.22
0.022
Gallstone
62 (14.4)
50 (14.4)
12 (14.4)
0.00
0.991
HBsAg
34 (7.9)
27 (7.9)
7 (7.9)
0.04
0.843
Increased Scr levels
3 (0.7)
3 (0.9)
0 (0.0)
-
-
Table 5 Distribution of prevalence of risk factors in patients with and without fatty liver
Patients with fatty liver (n = 430)
Patients without fatty liver (n = 495)
χ2
P value
All patients
Prevalence
All patients
Prevalence
Hypertriglyceridemia
135
31.40%
45
9.10%
73.04
< 0.001
Mixed type hyperlipidemia
90
20.90%
33
6.70%
40.61
< 0.001
Hypercholesterolemia
53
12.30%
95
19.20%
8.07
0.004
Hyperglycemia
76
17.70%
25
5.00%
37.70
< 0.001
Hypertension
69
16.00%
32
6.50%
21.72
< 0.001
Hyperuricemia
66
15.30%
14
2.80%
45.66
< 0.001
Citation: Liao XH, Cao X, Liu J, Xie XH, Sun YH, Zhong BH. Prevalence and features of fatty liver detected by physical examination in Guangzhou. World J Gastroenterol 2013; 19(32): 5334-5339