Predictive factors of endoscopic submucosal dissection procedure time for gastric superficial neoplasia

Table 1 Correlation analysis of numerical variables and endoscopic submucosal dissection time

Predictive factors	Data	ESD time (min)median (IQR)	Analysis method	P value
Age	mean ± SD	41.00 (39.00)	Pearson correlation	0.3135
	62.00 ± 11.69
Tumor size (cm2)	Median (IQR)	41.00 (39.00)	Pearson correlation	< 0.0001
	7.00 (8.82)
Proficiency level	n	ESD time per unit area(min)	Pearson correlation	< 0.0001
	1-183	5.00 ± 3.87

ESD: Endoscopic submucosal dissection; IQR: Interquartile-range.

Table 2 Categorical variables and endoscopic submucosal dissection time

Predictive factors	n (%)	ESD time (min)median (IQR)	Analysis method	P value
Location			Kruskal wallis	< 0.0001
Upper	44 (24.0)	52.00 (69.00)
Middle	52 (28.4)	48.00 (33.00)
Lower	87 (48.6)	26.00 (33.50)
Macroscopic appearance			Kruskal wallis	< 0.0001
Protrusion	76 (41.5)	23.00 (31.00)
Indentation	61 (33.3)	49.00 (31.00)
Mixed	46 (25.2)	50.00 (43.50)
Pathological type			Kruskal wallis	0.2410
Adenoma	36 (19.7)	25.00 (27.00)
HIN	97 (53.0)	29.00 (36.00)
Invasive carcinoma	50 (27.3)	51.00 (29.50)
Adhesion			Mann-whitney	0.0010
Yes	14 (7.7)	81.50 (149.00)
No	179 (92.3)	39.00 (35.00)
Gender			Mann-whitney	0.0210
Male	134 (73.2)	47.00 (41.00)
Female	49 (26.8)	29.00 (25.50)

ESD: Endoscopic submucosal dissection; IQR: Interquartile-range.

Table 3 Multivariable analysis of factors related to endoscopic submucosal dissection time

Predictive factors	Beta	Standardized coefficients beta	95%CI for beta	P value
Resection area	3.500	0.581	2.829-4.180	< 0.0001
Adhesion	67.082	0.356	47.003-86.285	< 0.0001
Location (upper)	39.439	0.345	25.767-50.124	< 0.0001
Proficiency level	-0.755	-0.207	-0.545-(-0.124)	0.0046
Location (middle)	7.009	0.059	-2.890-17.778	0.1408

ESD: Endoscopic submucosal dissection.