Transepithelial leak in Barrett's esophagus patients: The role of proton pump inhibitors

Table 1 Sucrose leak in Barrett's patients as a function of proton pump inhibitor use

	On PPIs	7 d off PPIs	7 d after PPI resumption
Median	87.8	101.9	63.0
mean ± SE	116.6 ± 16.5	142.7 ± 34.2	101.5 ± 21.0

Sucrose leak in Barrett’s esophagus patients (n = 14) on proton pump inhibitors (PPIs), following 7 d off PPIs, and after the reintroduction of PPIs for 7 d. The acute leak phenomenon observed in previous studies in PPI naїve patients is not seen with resumption of PPIs after 7 d. A statistical significance in sucrose leak is not demonstrated among the different groups (on PPIs vs off PPIs P = 0.497, off PPIs vs back on PPIs P = 0.323, on PPIs vs back on PPIs P = 0.574). SE: Standard error.