Neuroprotective action of Ginkgo biloba on the enteric nervous system of diabetic rats

Table 1 Final weight and glycemia in groups: control, diabetic and EGb 76-treated diabetic (mean ± SE)

Group	Final weight (g)	Blood glucose (mg/dL)
C	445.6 ± 63.04	78.97 ± 5.12
D	264.6 ± 22.88	253 ± 64.97
DT	308 ± 19.27	322 ± 20.42

n = 5/groups. C: Control; D: Diabetic; DT: EGb 76-treated diabetic.

Table 2 Neuronal density and mean area of cell bodies of myenteric and submucosal neurons in the jejunum of rat groups: control, diabetic and EGb 761-treated diabetic (mean ± SE)

Group	Myenteric plexus		Submucous plexus
	Neuronal density (cm2)	Mean area of cell body (μm2)	Neuronal density (cm2)	Mean area of cell body (μm2)
C	15 884 ± 712.0	234.2 ± 88.10	12 602 ± 233.8	230.6 ± 62.89
D	13 483 ± 617.9	245.6 ± 77.19	11 383 ± 159.6	235.4 ± 67.99
DT	14 426 ± 301.2	218.2 ± 72.10	12 682 ± 353.4	216.2 ± 62.03

n = 5/myenteric plexus group; n = 3/submucous plexus group. C: Control; D: Diabetic; DT: EGb 76-treated diabetic.

Table 3 Neuronal density and mean area of cell bodies of myenteric and submucosal neurons in the ileum of rat groups: control, diabetic and EGb 761-treated diabetic (mean ± SE)

Group	Myenteric plexus		Submucous plexus
	Neuronal density (cm²)	Mean area of cell body (μm²)	Neuronal density (cm²)	Mean area of cell body (μm²)
C	16 522 ± 625.5	232.7 ± 82.97	11 657 ± 403.9	210.0 ± 59.18
D	14 568 ± 424.7	251.4 ± 98.23	11 275 ± 281.9	231.3 ± 74.37
DT	16 884 ± 366.1	239.3 ± 81.19	11 943 ± 299.3	204.5 ± 57.36

n = 5/myenteric plexus group; n = 3/submucous plexus group. C: Control; D: Diabetic; DT: EGb 76-treated diabetic.