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©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Apr 28, 2011; 17(16): 2109-2112
Published online Apr 28, 2011. doi: 10.3748/wjg.v17.i16.2109
Published online Apr 28, 2011. doi: 10.3748/wjg.v17.i16.2109
Table 1 Serum matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 levels in patients and controls
| Variables | Controls (n = 50) | Patients (n = 100) | P |
| Age (yr) | 56 (48-65) | 58 (47-64) | |
| Gender female (%) | 37 | 40 | |
| MMP-1 (ng/mL) | 256 (109-342) | 785 (457-900) | < 0.0001 |
| TIMP-1 (ng/mL) | 220 (198-267) | 725 (417-1134) | < 0.0001 |
Table 2 Clinicopathological variables of serum matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in patients
| Variables | MMP-1 | TIMP-1 | P |
| Lymphovascular invasion | |||
| Negative | 543 (500-678) | 489 (450-573) | |
| Positive | 801 (768-845) | 642 (567-703) | < 0.001 |
| Tumor size (cm) | |||
| < 4 | 478 (460-501) | 429 (425-479) | |
| ≥ 4 | 675 (509-725) | 671 (532-690) | < 0.001 |
| Lymph node metastasis | |||
| Negative | 563 (503-650) | 642 (598-709) | |
| Positive | 742 (657-799) | 756 (570-876) | < 0.001 |
| T stage | |||
| T0-2 | 521 (498-599) | 598 (564-783) | |
| T3-4 | 674 (578-783) | 749 (570-794) | < 0.001 |
| TNM stage | |||
| I | 469 (458-502) | 476 (423-512) | |
| II | 534 (467-563) | 521 (478-589) | |
| III | 714 (546-857) | 753 (512-699) | < 0.001 |
| IV | 765 (699-900) | 975 (812-1134) | < 0.001 |
- Citation: Kemik O, Kemik AS, Sümer A, Dulger AC, Adas M, Begenik H, Hasirci I, Yilmaz O, Purisa S, Kisli E, Tuzun S, Kotan C. Levels of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 in gastric cancer. World J Gastroenterol 2011; 17(16): 2109-2112
- URL: https://www.wjgnet.com/1007-9327/full/v17/i16/2109.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i16.2109