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©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Apr 14, 2011; 17(14): 1817-1824
Published online Apr 14, 2011. doi: 10.3748/wjg.v17.i14.1817
Published online Apr 14, 2011. doi: 10.3748/wjg.v17.i14.1817
Table 1 Age and sex distribution of the 59 patients with multiple primary carcinoma included in this study
Gender | Age(yr) | |||||
n | Male | Female | Range | Mean | ≥ 55 | |
Esophageal MPC | 24 | 13 | 11 | 44-85 | 61.63 | 15/24 (62.5%) |
Esophageal and gastric MPC | 27 | 24 | 3 | 42-72 | 59.89 | 20/27 (74.07%) |
Gastric MPC | 8 | 7 | 1 | 48-76 | 64.38 | 7/8(87.5%) |
Table 2 Distance between every two esophageal lesions
Esophageal MPC | n (%) | Interval distance (cm) | |
Range | Mean | ||
Upper-middle | 12 (50.00) | 5-12.5 | 8.36 |
Upper-lower | 5 (20.83) | 8-13 | 11.20 |
Middle-lower | 7 (29.17) | 5-9 | 5.83 |
Table 3 Clinicopathological differences of esophageal lesions between esophageal multiple primary carcinoma and esophageal-gastric multiple primary carcinoma
EMPC | EGMPC | |||
Total (n = 49) | First lesion | Second or third lesion | (n = 27) | |
Location | ||||
Upper | 17 | 17 | 0 | 0 |
Middle | 19 | 7 | 12 | 16 |
Lower | 13 | 0 | 13 | 11 |
Largest dimension of lesions (cm) | ||||
mean ± SD1 | 4.33 ± 2.35 | 3.63 ± 1.96 | 5.00 ± 2.67 | 5.56 ± 2.34 |
95% CI | 3.63-5.02 | 2.80-4.45 | 3.90-6.10 | 4.63-6.48 |
Morphology | ||||
Hyperplastic | 23 | 11 | 12 | 11 |
Medullary | 9 | 4 | 5 | 7 |
Ulcerative | 7 | 5 | 2 | 5 |
Infiltrative | 7 | 3 | 4 | 2 |
Mixed | 3 | 0 | 3 | 2 |
Histology | ||||
Squamous cell carcinoma | 49 | 24 | 25 | 26 |
Sarcoma | 0 | 0 | 0 | 1 |
PT stage2 | ||||
T1 | 12 | 9 | 3 | 13 |
T2-4 | 37 | 15 | 22 | 14 |
Table 4 Clinicopathological differences of gastric lesions between gastric multiple primary carcinoma and esophageal-gastric multiple primary carcinoma
GMPC | EGMPC | |||
Total (n =16) | Main lesion | Additional lesion | (n = 27) | |
Location | ||||
Cardia | 8 | 1 | 7 | 16 |
Fundus | 0 | 0 | 0 | 1 |
Body | 3 | 3 | 0 | 3 |
Antrum | 5 | 4 | 1 | 7 |
Largest dimension of lesions (cm) | ||||
Mean ± SD1 | 2.94 ± 1.39 | 3.93 ± 1.21 | 1.94 ± 0.62 | 4.94 ± 2.63 |
95% CI | 2.20-3.68 | 2.93-4.95 | 1.42-2.46 | 3.90-5.98 |
Morphology | ||||
Hyperplastic | 13 | 5 | 8 | 17 |
Ulcerative | 1 | 1 | 0 | 6 |
Infiltrative | 2 | 2 | 0 | 4 |
Histology | ||||
Squamous cell carcinoma | 0 | 0 | 0 | 4 |
Adenocarcinoma | 16 | 8 | 8 | 23 |
PT stage2 | ||||
T1 | 6 | 1 | 5 | 3 |
T2~4 | 10 | 7 | 3 | 24 |
Table 5 Clinicopathological characteristics of 19 misdiagnosed synchronous multiple primary carcinomas
Type | Age | Gender | Largest dimension (cm) | Location of lesion | PT stage | ||
Diagnosed | Missed | Diagnosed | Missed | ||||
1 EMPC | 49 | Female | 3.3 | 2.2 | Middle | Lower | T4/T1 |
2 EMPC | 58 | Male | 3.4 | 1 | Lower | Upper | T2/T1 |
3 EMPC | 67 | Male | 4.7 | 2.5 | Middle | Lower | T3/T1 |
4 EMPC | 73 | Female | 5.5 | 1.8 | Middle | Upper | T3/T1 |
5 EMPC | 64 | Male | 6.2 | 2 | Lower | Upper | T2/T1 |
6 EMPC | 57 | Male | 4.5 | 1,5 | Lower | Middle | T2/T1 |
7 EGMPC | 65 | Female | 6.5 | 2.2 | Lower | Body | T4/T2 |
8 EGMPC | 54 | Male | 5.5 | 2.5 | Lower | Fundus | T3/T1 |
9 EGMPC | 58 | Male | 4.5 | 1.8 | Cardia | Middle | T3/T1 |
10 EGMPC | 62 | Male | 3.2 | 2.8 | Cardia | Middle | T3/T1 |
11 EGMPC | 72 | Male | 3.5 | 5.7 | Cardia | Lower | T4/T3 |
12 EGMPC | 63 | Male | 4.2 | 3.2 | Lower | Antrum | T2/T1 |
13 EGMPC | 70 | Male | 2.8 | 2.5 | Cardia | Middle | T2/T1 |
14 EGMPC | 60 | Male | 4.2 | 2 | Antrum | Middle | T3/T1 |
15 EGMPC | 60 | Male | 4.2 | 2.2 | Cardia | Middle | T3/T1 |
16 EGMPC | 57 | Male | 4.5 | 3.5 | Lower | Cardia | T3/T3 |
17 GMPC | 52 | Male | 2.2 | 2.8 | Cardia | Antrum | T2/T1 |
18 GMPC | 57 | Male | 4.5 | 1.2 | Antrum | Cardia | T3/T1 |
19 GMPC | 64 | Male | 5.5 | 2.2 | Antrum | Cardia | T3/T1 |
- Citation: Yang ZH, Gao JB, Yue SW, Guo H, Yang XH. X-ray diagnosis of synchronous multiple primary carcinoma in the upper gastrointestinal tract. World J Gastroenterol 2011; 17(14): 1817-1824
- URL: https://www.wjgnet.com/1007-9327/full/v17/i14/1817.htm
- DOI: https://dx.doi.org/10.3748/wjg.v17.i14.1817