Comparison between surgical outcomes of colorectal cancer in younger and elderly patients

Table 1 Clinicopathological data of the patients with colorectal adenocarcinoma n (%)

		Younger group (n = 68)	Elderly group (n = 54)	P value
Sex				NS
Male/female		40 (58.8)/28 (41.2)	28 (51.9)/26 (48.1)
Age (yr) (mean ± SD)		62.2 ± 8.6	80.4 ± 5.0	NS
BMI (kg/m2) (mean ± SD)		22.2 ± 3.3	21.1 ± 3.6	0.035
Localization of tumor lesion				NS
C		3 (4.4)	3 (5.6)
A		9 (13.2)	18 (33.3)
T		8 (11.8)	8 (14.8)
D		3 (4.4)	1 (1.9)
S		26 (38.2)	11 (20.4)
R		20 (29.4)	14 (25.9)
ASA				0.01
I		39 (57.4)	12 (22.2)
II		22 (32.4)	31 (57.4)
III		6 (8.8)	11 (20.4)
IV		1 (1.5)	0 (0)
Type of tumor				NS
0		6 (8.8)	1 (1.9)
1		6 (8.8)	7 (13.0)
2		52 (76.5)	44 (81.5)
3		5 (7.4)	4 (7.4)
Histological type				NS
Papillary adenocarcinoma		1 (1.5)	2 (3.7)
Tubular adenocarcinoma (tub1/tub2)		29 (42.6)/33 (48.5)	17 (31.5)/28 (51.9)
Poorly differentiated adenocarcinoma		3 (4.4)	5 (9.3)
Mucinous adenocarcinoma		2 (2.9)	2 (3.7)
T Stage				NS
T1 (m, sm)		0 (0)/7 (10.3)	1 (1.9)/2 (3.7)
T2 (mp)		15 (22.1)	8 (14.8)
T3 (ss, a)		16 (23.5)/14 (20.6)	19 (35.2)/9 (16.7)
T4 (se, si, ai)		13 (19.1)/3 (4.4)/0 (0)	11 (20.4)/4 (7.4)/0 (0)
N Stage				NS
N0		39 (57.4)	30 (55.6)
N1		21 (30.9)	13 (24.1)
N2		4 (5.9)	5 (9.3)
NX		4 (5.9)	6 (11.1)
Metastases				NS
M0		61 (89.7)	49 (90.7)
M1		7 (10.3)	5 (9.3)
Stage				NS
0		0 (0)	1 (1.9)
I		17 (25.0)	8 (14.8)
II		20 (29.4)	22 (40.7)
III		23 (33.8)	17 (31.5)
IV		8 (11.8)	6 (11.1)
Comorbidity
Overall	Present	27 (39.7)	36 (66.7)	0.003
	Absent	41 (60.3)	18 (33.3)
Cardiovascular diseases	Present	6 (8.8)	14 (25.9)	0.011
	Absent	62 (91.2)	40 (74.1)
Hypertension	Present	10 (14.7)	19 (35.2)	0.008
	Absent	58 (85.3)	35 (64.8)
Diabetes mellitus	Present	5 (7.4)	3 (5.6)	NS
	Absent	63 (92.6)	51 (94.4)
Cerebrovascular diseases	Present	3 (4.4)	5 (9.3)	NS
	Absent	65 (95.6)	49 (90.7)
Other diseases	Present	6 (8.8)	7 (13.0)	NS
	Absent	62 (91.2)	47 (87.0)

BMI: Body mass index; NS: Not significant; C: Cecum colon; A: Ascending colon; T: Transverse colon; D: Descending colon; R: Rectal colon.

Table 2 Data related to surgical treatment of patients with colorectal adenocarcinoma between the two groups (mean ± SD) n (%)

	Younger group (n = 68)	Elderly group (n = 54)	P value
Tumor size index (cm2)	15.7 ± 12.0	22.8 ± 20.2	NS
Lesion circulation (%)	74.0 ± 26.9	75.3 ± 27.7	NS
Operation time (min)	137.4 ± 45.7	120.4 ± 35.1	NS
Operative blood loss (mL)	138.4 ± 166.2	140.4 ± 198.8	NS
Postoperative stay (d)	23.2 ± 14.3	24.6 ± 14.5	NS
Blood transfusion			0.001
Yes	0 (0)	8 (14.8)
No	68 (100.0)	46 (85.2)
Procedure of surgery			NS
Cecum resection	1 (1.5)	0 (0)
Right hemicolectomy	16 (23.5)	24 (44.4)
Transverse colon resection	2 (2.9)	4 (7.4)
Left hemicolectomy	4 (5.9)	4 (7.4)
Sigmoid colectomy	22 (32.4)	9 (16.7)
Anterior resection	16 (23.5)	9 (16.7)
Hartmann’s resection	2 (2.9)	0 (0)
Mile’s resection	5 (7.4)	4 (7.4)
Lymph node dissection			NS
D0	4 (5.9)	7 (13.0)
D1	10 (14.7)	7 (13.0)
D2	31 (45.6)	30 (55.6)
D3	23 (33.8)	10 (18.5)
Number of lymph nodes resected	12.1 ± 9.0	11.3 ± 8.6	NS
Distal margin distance (mm)	61.0 ± 40.4	62.2 ± 40.9	NS
Proximal margin distance (mm)	96.8 ± 47.6	93.4 ± 57.9	NS
Morbidity			NS
Surgical site infection			NS
Yes	5 (7.4)	7 (13.0)
No	63 (92.6)	47 (87.0)
Anastomotic leakage			NS
Yes	4 (5.9)	3 (5.6)
No	64 (94.1)	51 (94.4)
Others			NS
Yes	8 (11.8)	6 (11.1)
No	60 (88.2)	48 (88.9)

NS: Not significant.