Brief Article
Copyright ©2011 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Mar 28, 2011; 17(12): 1642-1648
Published online Mar 28, 2011. doi: 10.3748/wjg.v17.i12.1642
Comparison between surgical outcomes of colorectal cancer in younger and elderly patients
Longxue Jin, Norio Inoue, Naoki Sato, Susumu Matsumoto, Hitoshi Kanno, Yuko Hashimoto, Kazuhiro Tasaki, Kinya Sato, Shun Sato, Katsutoshi Kaneko
Longxue Jin, Norio Inoue, Naoki Sato, Susumu Matsumoto, Hitoshi Kanno, Center for Digestive Diseases, Northern Fukushima Medical Center, Fukushima, 960-0502, Japan
Yuko Hashimoto, Kazuhiro Tasaki, Department of Pathology, Fukushima Medical University Hospital, Fukushima, 960-1295, Japan
Kinya Sato, Shun Sato, Katsutoshi Kaneko, Division of Anesthesiology, Northern Fukushima Medical Center, Fukushima, 960-0502, Japan
Author contributions: Jin L and Inoue N designed the research; Jin L, Kanno H, Hashimoto Y, Tasaki K, Sato K, Sato S and Kaneko K collected the data; Jin L, Inoue N, Matsumoto S and Sato N analyzed the data; Jin L and Inoue N wrote the paper.
Correspondence to: Longxue Jin, MD, PhD, Center for Digestive Diseases, Northern Fukushima Medical Center, Hakozakiazahigashi 23-1, Date City, Fukushima, 960-0502, Japan. longxuejin@hotmail.com
Telephone: +81-24-5510551 Fax: +81-24-5510808
Received: August 9, 2010
Revised: December 13, 2010
Accepted: December 20, 2010
Published online: March 28, 2011
Abstract

AIM: To compare the outcome of surgical treatment of colorectal adenocarcinoma in elderly and younger patients.

METHODS: The outcomes of 122 patients with colorectal adenocarcinoma who underwent surgical treatment between January 2004 and June 2009 were analyzed. The clinicopathological and blood biochemistry data of the younger group (< 75 years) and the elderly group (≥ 75 years) were compared.

RESULTS: There were no significant differences between the two groups in operation time, intraoperative blood loss, hospital stay, time to resumption of oral intake, or morbidity. The elderly group had a significantly higher rate of hypertension and cardiovascular disease. The perioperative serum total protein and albumin levels were significantly lower in the elderly than in the younger group. The serum carcinoembryonic antigen level was lower in the elderly than in the younger group, and there was a significant decreasing trend after the operation in the elderly group.

CONCLUSION: The short-term outcomes of surgical treatment in elderly patients with colorectal adenocarcinoma were acceptable. Surgical treatment in elderly patients was considered a selectively effective approach.

Keywords: Colorectal tumor, Elderly patient, Morbidity, Carcinoembryonic antigen, C-reactive protein