Shape of Barrett’s epithelium is associated with prevalence of erosive esophagitis

Table 1 Clinical characteristics of patients enrolled in the present study

Clinical characteristics	n (%)
Total patients	869
Patient profiles
Age
median; range (yr)	66; 29-91
Sex
Female (%)	406 (46.7)
BMI
median; range	22.2; 13.5-41.2
Regular drinking habit (%)	316 (36.4)
Smoking habit (%)	319 (36.7)
Endoscopic results
Hiatal hernia (%)	266 (30.6)
GMA
Open type (%)	466 (53.6)
Erosive esophagitis
Total (%)	165 (19.0)
Mild (LA class A, B) (%)	152 (17.5)
Severe (LA class C, D) (%)	13 (1.5)
Barrett’s epithelium
Total (%)	374 (43.0)
SSBE (%)	370 (42.6)
LSBE (%)	4 (0.5)

GMA: Gastric mucosal atrophy; LA: Los Angeles; SSBE: Short-segment Barrett’s esophagus; LSBE: Long-segment Barrett’s esophagus.

Table 2 Clinical characteristics of patients according to the two shapes of Barrett’s epithelium n (%)

	Shape of Barrett’s epithelium		P value
	L type (n = 353)	F type (n = 21)
				Age
Median; range (yr)	68; 31-91	68; 54-80	0.8532
Sex
Female (%)	154 (43.6)	9 (42.9)	0.94501
BMI
Median; range	22.5; 14.4-41.2	22.0; 18.1-30.5	0.8565
Regular drinking habit (%)	144 (40.8)	13 (61.9)	0.05681
Smoking habit (%)	160 (45.3)	14 (66.7)	0.05681
Hiatal hernia (%)	145 (41.1)	8 (38.1)	0.96692
GMA
Open type (%)	184 (52.1)	5 (23.8)	0.02162
Erosive esophagitis (%)
Total	112 (31.7)	13 (61.9)	0.00441
Mild	103 (29.2)	9 (42.9)	0.27872
Severe	9 (2.5)	4 (19.0)	0.00073

P value: Mann–Whitney U test;

¹: χ² test;

²: χ² test (Yates’ correction);

³: Fisher’s exact test.

Table 3 Clinical characteristics of patients according to the two lengths of Barrett’s epithelium n (%)

	The C extent of Barrett’s epithelium		P value
	< 2 cm (n = 347)	≥ 2 cm (n = 27)
Age
Median; range (yr)	68; 31–91	70; 42–86	0.4933
Sex
Female (%)	149 (42.9)	14 (51.9)	0.36831
BMI
Median; range	22.5; 14.4–41.2	22.3; 16.9–28.2	0.7199
Regular drinking habit (%)	143 (41.2)	14 (51.9)	0.28051
Smoking habit (%)	161 (46.4)	13 (48.1)	0.86061
Hiatal hernia (%)	136 (39.2)	17 (63.0)	0.01551
GMA
Open type (%)	177 (51.0)	12 (44.4)	0.51111
Erosive esophagitis (%)
Total	109 (31.4)	16 (59.3)	0.00311
Mild	97 (28.0)	15 (55.6)	0.00261
Severe	12 (3.5)	1 (3.7)	> 0.99992

P value: Mann–Whitney U test;

¹: χ² test;

²: Fisher’s exact test.