Anti-inflammatory effects of Mangifera indica L. extract in a model of colitis

Table 1 Experimental design of dextran sulfate sodium-induced colitis model

Group	Treatment regimens			n
	Week 1	Week 2	Week 3
Control	Vehicle po	Vehicle po	DSS no + vehicle	4
A	Vehicle po	Vehicle po	DSS yes + vehicle	8
B	Vehicle po	Vehicle po	DSS yes + MIE 150 mg/kg rectal	8
C	MIE 150 mg/kg po	MIE 150 mg/kg po	DSS yes + MIE 150 mg/kg rectal	8

MIE: Mangifera indica L.; DSS: Dextran sulfate sodium.

Table 2 Serum levels of tumor necrosis factor-α and interleukin-6 in experimental groups

Group	TNF-α	IL-6
A	146.17 ± 13.1	118.15 ± 16.7
C	101.92 ± 9.3a	61.36 ± 18.8a

Results are presented as % of control group, mean ± SE of each group.

^aP < 0.05 (n = 8 in both groups). TNF-α: Tumor necrosis factor-α; IL-6: Interleukin-6.