Copyright
©2010 Baishideng.
World J Gastroenterol. May 21, 2010; 16(19): 2428-2434
Published online May 21, 2010. doi: 10.3748/wjg.v16.i19.2428
Published online May 21, 2010. doi: 10.3748/wjg.v16.i19.2428
Table 1 Parameters of patients (n = 68)
Parameters | n (%) |
Age (yr) | |
< 60 | 30 (44.1) |
≥ 60 | 38 (55.9) |
Gender | |
Male | 38 (55.9) |
Female | 30 (44.1) |
Tumor site | |
Left hemicolon | 45 (66.2) |
Right hemicolon | 23 (33.8) |
Pathological grade | |
G1 | 10 (14.7) |
G2 | 51 (75.0) |
G3 | 7 (10.3) |
Survival time (mo) | |
≥ 60 | 52 (76.5) |
< 60 | 16 (23.5) |
Table 2 Relation between expression of calreticulin, infiltration of lymphocytes and parameters of patients (n = 68)
Parameters | Calreticulin expression | P | |
(-) | (+)-(+++) | ||
Gender | 0.813 | ||
Male | 15 | 23 | |
Female | 11 | 19 | |
Age (yr) | 0.204 | ||
≥ 60 | 12 | 26 | |
< 60 | 14 | 16 | |
Tumor site | 0.245 | ||
Left hemicolon | 15 | 30 | |
Right hemicolon | 11 | 12 | |
Pathological grade | 0.643 | ||
G1 | 5 | 5 | |
G2 | 19 | 32 | |
G3 | 2 | 5 | |
Infiltration of CD3+ cells per high-power field | 0.387 | ||
> 18 | 18 | 33 | |
≤ 18 | 8 | 9 | |
Infiltration of CD45RO+ cells per high-power field | 0.010 | ||
> 26 | 15 | 36 | |
≤ 26 | 11 | 6 |
Table 3 Univariate survival analysis (n = 68)
Parameters | Survival time (mo) | P | |
<60 | ≥ 60 | ||
Gender | 0.542 | ||
Male | 10 | 28 | |
Female | 6 | 24 | |
Age (yr) | 0.973 | ||
≥ 60 | 9 | 29 | |
< 60 | 7 | 23 | |
Tumor sites | 0.722 | ||
Left hemicolon | 10 | 35 | |
Right hemicolon | 6 | 17 | |
Pathological grade | 0.919 | ||
G1 | 2 | 8 | |
G2 | 12 | 39 | |
G3 | 2 | 5 | |
Infiltration of CD3+ cells per high-power field | 0.000 | ||
> 18 | 6 | 45 | |
≤ 18 | 10 | 7 | |
Infiltration of CD45RO+ cells per high-power field | 0.000 | ||
> 26 | 5 | 46 | |
≤ 26 | 11 | 6 | |
Calreticulin expression | |||
(-) | 10 | 16 | |
(+)-(+++) | 6 | 36 | 0.022 |
Table 4 Multivariate survival analysis (n = 68)
Parameters | B | SE | Wald | df | Sig. | Exp(B) | 95% CI for Exp (B) | |
Lower | Upper | |||||||
Pathological grade | 0.172 | 0.261 | 0.435 | 1 | 0.510 | 1.188 | 0.712 | 1.979 |
Gender | -0.027 | 0.247 | 0.012 | 1 | 0.912 | 0.973 | 0.599 | 1.580 |
Age | 0.079 | 0.255 | 0.095 | 1 | 0.758 | 1.082 | 0.656 | 1.784 |
Tumor site | 0.085 | 0.276 | 0.094 | 1 | 0.759 | 0.919 | 0.535 | 1.579 |
Infiltration of CD3+ cells | -0.057 | 0.511 | 0.013 | 1 | 0.911 | 0.944 | 0.347 | 2.537 |
Infiltration of CD45RO+ cells | -0.743 | 0.552 | 1.809 | 1 | 0.179 | 0.476 | 0.161 | 1.404 |
Expression level of calreticulin | 0.133 | 0.279 | 0.226 | 1 | 0.634 | 0.876 | 0.507 | 1.512 |
- Citation: Peng RQ, Chen YB, Ding Y, Zhang R, Zhang X, Yu XJ, Zhou ZW, Zeng YX, Zhang XS. Expression of calreticulin is associated with infiltration of T-cells in stage IIIB colon cancer. World J Gastroenterol 2010; 16(19): 2428-2434
- URL: https://www.wjgnet.com/1007-9327/full/v16/i19/2428.htm
- DOI: https://dx.doi.org/10.3748/wjg.v16.i19.2428