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©2010 Baishideng.
World J Gastroenterol. Apr 21, 2010; 16(15): 1871-1878
Published online Apr 21, 2010. doi: 10.3748/wjg.v16.i15.1871
Published online Apr 21, 2010. doi: 10.3748/wjg.v16.i15.1871
Table 1 Baseline data of study patients
Group | Age (yr) | Sex (n) M/F | Tumor (n) mal/non mal | Fibrosis (n) none/mod/sev | Steatosis (n) none/min/mod/sev |
Control (A) (n = 30) | 57 ± 14 (26-81) | 18/12 | 26/4 | 10/15/5 | 8/16/5/1 |
IP (B) (n = 31) | 55 ± 13 (28-77) | 19/12 | 28/3 | 12/14/5 | 10/14/5/2 |
P-value | 0.61 | 0.92 | 0.65 | 0.39 | 0.39 |
Table 2 No differences in the intraoperative data of the 2 groups of patients
Group | OP time (min) mean/range | PM time (min) mean/range | LR time (min) mean/range | LV resected (mL) mean/range | Segments resected (n) mean/range |
Control (A) (n = 30) | 260 ± 63 (170-420) | 34 ± 14 (15-82) | 30 ± 10 (10-50) | 390 ± 303 (80-1400) | 2.7 ± 1.3 (1-5) |
IP (B) (n = 31) | 271 ± 58 (180-420) | 33 ± 12 (8-67) | 31 ± 11 (15-56) | 426 ± 453 (30-2000) | 2.7 ± 1.1 (1-5) |
P-value | 0.36 | 0.70 | 0.83 | 0.77 | 0.69 |
Table 3 Flow characteristics of patients undergoing PM (control, n = 30) and IP + PM (study group, n = 31)
Group | Vessel | Baseline (mL/min) | After IP (mL/min) | 15 min (mL/min) | Before abd. closure (mL/min) |
Control | HA | 141 ± 24 | - | 152 ± 29 | 146 ± 18 |
IP | HA | 126 ± 19 | 263 ± 51 | 196 ± 38a | 174 ± 22a |
Control | PV | 1023 ± 130 | - | 726 ± 121 | 757 ± 58 |
IP | PV | 930 ± 94 | 920 ± 81 | 919 ± 75a | 949 ± 62a |
Total (Co) | HA + PV | 1164 ± 72 | - | 878 ± 77 | 903 ± 37c |
Total (IP) | HA + PV | 1056 ± 53 | 1183 ± 64 | 1115 ± 49b | 1123 ± 58b |
Table 4 Outcome data of patients undergoing liver resection with PM (A) or with IP + PM (B)
Group | RPC (units) mean/range | ALT (U/L) mean/range | Bilirubin (mg/dL) mean/range | LF (n) transient/fatala | Biliary compl. (n) major/minor |
Control (A) (n = 30) | 0.90 ± 1.24 (0-5) | 550 ± 650 (54-2888) | 1.73 (0.40-9.83) | 2 (2) | 2b (4) |
IP (B) (n = 31) | 0.47 ± 1.31 (0-6) | 247 ± 210 (45-852) | 1.40 ± 1.26 (0.23-5.59) | 0 (1) | 1 (2) |
P-value | 0.014 | 0.04 | 0.69 | 0.04 | 0.04 |
Table 5 Factors predicting occurrence of postoperative complications by multivariate logistic regression (backward selection) of factors of importance or significance on univariate analysis
Analysis (P-value) | IP treatment | Length of PM | Resected LV | HA flow | PV flow | Liver steatosis | Liver fibrosis |
Univariate | 0.038 | 0.043 | 0.067 | 0.044 | 0.72 | 0.81 | 0.94 |
Multivariate | 0.047 | 0.022 | NS | NS | NS | NS | NS |
- Citation: Heizmann O, Meimarakis G, Volk A, Matz D, Oertli D, Schauer RJ. Ischemic preconditioning-induced hyperperfusion correlates with hepatoprotection after liver resection. World J Gastroenterol 2010; 16(15): 1871-1878
- URL: https://www.wjgnet.com/1007-9327/full/v16/i15/1871.htm
- DOI: https://dx.doi.org/10.3748/wjg.v16.i15.1871