Solid pseudopapillary tumor of the pancreas: A review of 553 cases in Chinese literature

Table 1 Symptoms of SPT patients (n = 473)

Symptoms	Patients (n)	%
Abdominal pain	178	37.63
Abdominal mass	170	35.94
Abdominal discomfort	155	32.77
Asymptomatic	150	31.70
Vomiting	25	5.29
Post-trauma	23	4.86
Nausea	19	4.01
Back pain	17	3.59
Jaundice	17	3.59
Anorexia	11	2.33
Weight loss	9	1.90
Fever	7	1.48
Other symptoms	5	1.06

SPT: Solid pseudopapillary tumor.

Table 2 Surgical procedures for 315 SPT patients

Operation	Patients (n)	%
Local resection or enucleation	104	33.02
Distal pancreatectomy	99	31.43
Pancreatoduodenectomy	81	25.71
Central pancreatectomy	19	6.03
Total pancreatectomy	2	0.63
Palliative operation	10	3.17
Portal vein reconstruction	3	0.95

Table 3 Immunohistochemical parameters of SPT

Antigen	Patients (n)	Positivity, n (%)
AAT	276	261 (94.6)
Vim	289	269 (93.1)
AACT	237	215 (90.7)
NSE	221	179 (81.0)
CD56	43	29 (67.4)
CD10	51	33 (64.7)
PR	157	89 (56.7)
Ki67	12	5 (41.7)
Syn	196	83 (42.3)
CK	213	66 (31.0)
CgA	193	45 (23.3)
ER	97	11 (11.3)

AAT: a1-antitrypsin; Vim: Vimentin; AACT: a1-antichymotrypsin; NSE: Neuron specific enolase; PR: Progesterone receptor; Syn: Synaptophysin; CK: Cytokeratin; CgA: Chromogranin A; ER: Estrogen receptor.

Table 4 Clinicopathological features and outcome of SPT

Author	n	Female/male	Median/mean age(yr)	Size (cm)	Surgical treatment	Median/mean follow-up (mo)	Outcome
Zhang et al[5]	29	26/3	26.5	8.7 (2-15)	5 PD, 6 DP+S, 15 LR, 1 ID	2-84	28 alive, 1 dead
Cheng et al[6]	22	22/0	27.3 (11-65)	9.5 (2.5-25)	11PD, 2CP, 9LR	NA	22 alive, 0 recurred
Zhong et al[7]	20	18/2	25.3 (13-48)	8.2 (3-17)	5PD, 4DP+S, 9EN, 2PO	44.4 (9-120)	14 alive, 3 dead, 3 lost
Wang et al[8]	16	15/1	34.6 (15-58)	5.6 (2-15)	6PD, 1LR, 3DP, 6DP+S	34.6	15 alive, 1 lost
Zhu et al[9]	14	13/1	11.4 (9-14)	7.0 (3-15)	7PD, 5DP+S, 2LR	46.6 (1-192)	14 alive, 0 recurred

PD: Pancreaticoduodenectomy; DP: Distal pancreatectomy; LR: Local resection; ID: Internal drainage; CP: Central pancreatectomy; EN: Enucleation; PO: Palliative operation; S: Splenectomy.