Clinical application of hepatic CT perfusion

Table 1 Perfusion parameters of normal liver from different sources

Sources (n)	HAP	PVP	HPI	HBF	HBV	MTT
Miles et al[2] (5)	0.17	0.34	32%
Blomley et al[3]	0.191	0.932
Weidekamm et al[4] (24)	0.2 ± 0.08	1.02 ± 0.35
Zhou et al[5] (4)	0.17 ± 0.08	0.9 ± 0.04	16 ± 16%	106.24 ± 54.53	20.24 ± 8.26	15.06 ± 8.94
Hashimoto et al[6] (10)			18.4 ± 5.6%	103.9 ± 18	12.5 ± 2.0	11.1 ± 1.6

¹n = 31,

²n = 19; HAP: Hepatic arterial perfusion (mL/min per millilitre); PVP: Portal vein perfusion (mL/min per millilitre); HPI: Hepatic arterial perfusion index (%); HBF: Hepatic blood flow (mL/min per 100 g); HBV: Hepatic blood volume (mL/100 g); MTT: Mean transit time (s).

Table 2 Changes of perfusion parameters in some liver diseases

Liver disease	Sources	Object	n	HAP	PVP	HPI	HBF	HBV	MTT
Chronic	Guan et al[7]	Rat	14			↑	↓	↓	↑
Liver	Van Beers et al[8]	Patient	34			↑			↑
Disease	Hashimoto et al[6]	Patient	38			↑
Primary	Zhou et al[5]	Patient	62	↑		↑	↑
Hepatic	Tsushima et al[11]	Patient	11	↑
Carcinoma	Komemushi et al[12]	Patient	37				↑	↑
	Sahani et al[13]	Patient	25				↑	↑	↓
Liver	Miles et al[2]	Patient	4	↑		↑
Metastatic	Tsushima et al[11]	Patient	17	↑
Disease	Leggett et al[16]	Patient	20	↑
	Shi et al[18]	Rat	19	↑	↓

↑: Increased; ↓: Decreased.