Bae RC, Jeon SW, Cho HJ, Jung MK, Kweon YO, Kim SK. Gastric dysplasia may be an independent risk factor of an advanced colorectal neoplasm. World J Gastroenterol 2009; 15(45): 5722-5726 [PMID: 19960571 DOI: 10.3748/wjg.15.5722]
Corresponding Author of This Article
Seong Woo Jeon, Assistant Professor, Department of Internal Medicine, Kyungpook National University Hospital, 50 Samduk 2-ga, Chung-gu, Daegu 700-721, South Korea. sw-jeon@hanmail.net
Article-Type of This Article
Brief Article
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World J Gastroenterol. Dec 7, 2009; 15(45): 5722-5726 Published online Dec 7, 2009. doi: 10.3748/wjg.15.5722
Table 1 Baseline characteristics of gastric dysplasia and control group
Gastric dysplasia (n = 133)
Control (n = 213)
P-value
Age (mean ± SD)
61.2 ± 9.7
49.6 ± 8.3
0.0005
Sex [M/F, (%)]
97/36 (73/37)
162/51 (76/24)
0.5200
H pylori
0.2610
(+) n = 204
73
131
(-) n = 142
60
82
Colorectal adenoma
0.5220
(+) n = 148
55
93
(-) n = 198
78
120
Advanced adenoma
0.0007
(+) n = 44
28
16
(-) n = 302
105
197
Table 2 Baseline characteristics of advanced adenoma (+) and (-) group
Advanced adenoma (+) (n = 44)
Advanced adenoma (-) (n = 302)
P-value
Age (mean ± SD)
60.8837 ± 8.55294
53.1419 ± 10.43410
0.0002
Sex [M/F n (%)]
38/6 (86/14)
221/81 (73/27)
0.0600
H pylori
0.1060
(+) n = 204
21
183
(-) n = 142
23
119
Table 3 Statistics of colorectal adenoma and advanced adenoma groups
Colorectal adenoma
Advanced adenoma
aOR
CI
P-value
aOR
CI
P-value
Age (old age)
1.337
0.872-2.049
0.0020
2.872
1.446-5.704
0.0002
Sex (female)
0.629
0.379-1.042
0.0800
0.431
0.176-1.057
0.0640
H pylori (positive)
1.037
0.672-1.599
0.9120
0.594
0.315-1.120
0.1390
G. dysplasia (presence)
0.910
0.587-1.411
0.7380
3.283
1.700-6.342
0.0004
Table 4 Multivariate analysis of colorectal adenoma and advanced adenoma groups
Colorectal adenoma
Advanced colorectal adenoma
B
SE
t
Sig
95% CI
B
SE
t
Sig
95% CI
Age
3.585
1.129
3.176
0.0020
1.365 to 5.805
7.770
1.648
4.714
0.0002
4.529 to 11.01
Sex
-0.085
0.047
-1.810
0.0710
-0.007 to 0.178
-0.132
0.070
1.888
0.0600
-0.269 to -0.006
H pylori
-0.009
0.054
-0.163
0.8710
-0.114 to 0.097
-0.129
0.079
1.623
0.1060
-0.285 to -0.027
G. dysplasia
0.022
0.053
0.421
0.6740
-0.082 to 0.127
0.289
0.077
3.741
0.0004
0.137 to 0.440
Citation: Bae RC, Jeon SW, Cho HJ, Jung MK, Kweon YO, Kim SK. Gastric dysplasia may be an independent risk factor of an advanced colorectal neoplasm. World J Gastroenterol 2009; 15(45): 5722-5726