Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice

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Apr 28, 2009 (publication date) through Feb 7, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2009; 15(16): 1943-1950
Published online Apr 28, 2009. doi: 10.3748/wjg.15.1943

Table 1 Silibinin reduced the frequency and volume of HuH7 xenografts in nude mice

Groups	Treatment	Tumor frequency (%)	Tumor volume (cm³)
Group 1	Placebo	100	4.0 ± 0.9
Group 2	80 mg/kg per day	50^a	2.1 ± 0.3^a
Group 3	160 mg/kg per day	30^a	0.6 ± 0.2^a

^aP < 0.05 vs Group 1, n = 10/group.

Citation: Cui W, Gu F, Hu KQ. Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice. World J Gastroenterol 2009; 15(16): 1943-1950
URL: https://www.wjgnet.com/1007-9327/full/v15/i16/1943.htm
DOI: https://dx.doi.org/10.3748/wjg.15.1943

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