Pancreatic carcinoma coexisting with chronic pancreatitis versus tumor-forming pancreatitis: Diagnostic utility of the time-signal intensity curve from dynamic contrast-enhanced MR imaging

Table 1 Clinicopathological characteristics and pancreatic TIC profiles in patients with focal pancreatic mass due to pancreatic carcinoma

			Locationof focalmass		Underlyingchronicpancreatitis		Type of pancreatic TIC of			Histopathology of
				Preoperative		operative	proximal	focal	distal	proximal	focal	distal
Case No.	Age	Sex		diagnosis		procedure	pancreas	mass	pancreas	pancreas	mass	pancreas
1	53	M	Ph	Carcinoma	No	PD	I	III	I	Normal	IDC	Normal
2	64	M	Ph	Carcinoma	No	PD	I	III	I	Normal	IDC	Normal
3	73	F	Ph	Carcinoma	No	PD	I	III	II	Normal	IDC	TACP
4	52	F	Ph	Carcinoma	No	PD	I	III	II	Normal	IDC	TACP
5	69	M	Ph	Carcinoma	No	PPPD	I	III	II	Normal	IDC	TACP
6	70	F	Ph	Carcinoma	No	PPPD	I	III	II	Normal	IDC	TACP
7	53	M	Ph	Carcinoma	No	PPPD	I	III	II	Normal	IDC	TACP
8	78	F	Ph	Carcinoma	No	PPPD	I	III	II	Normal	IDC	TACP
9	57	M	Ph	Carcinoma	No	PPPD	I	III	II	Normal	IDC	TACP
10	59	F	Pb	Carcinoma	No	DP	I	III	II	Normal	IDC	TACP
11	75	F	Pb	Carcinoma	No	DP	I	III	II	Normal	IDC	TACP
12	75	F	Pb	Carcinoma	No	DP	I	III	II	Normal	IDC	TACP
13	54	F	Ph	Carcinoma	No	PD	I	IV	I	Normal	IDC	Normal
14	63	M	Ph	Carcinoma	No	PPPD	I	IV	I	Normal	IDC	Normal
15	57	F	Ph	Carcinoma	No	PPPD	I	IV	I	Normal	IDC	Normal
16	67	M	Ph	Carcinoma	No	PD	I	IV	II	Normal	IDC	TACP
17	67	M	Ph	Carcinoma	No	PD	I	IV	II	Normal	IDC	TACP
18	59	M	Ph	Carcinoma	No	PD	I	IV	II	Normal	IDC	TACP
19	74	M	Ph	Carcinoma	No	PD	I	IV	II	Normal	IDC	TACP
20	69	M	Ph	Carcinoma	No	PD	I	IV	II	Normal	IDC	TACP
21	73	M	Ph	Carcinoma	No	PD	I	IV	II	Normal	IDC	TACP
22	74	M	Ph	Carcinoma	No	PPPD	I	IV	II	Normal	IDC	TACP
23	61	M	Ph	Carcinoma	No	PPPD	I	IV	II	Normal	IDC	TACP
24	64	F	Ph	Carcinoma	No	PPPD	I	IV	II	Normal	IDC	TACP
25	63	M	Ph	Carcinoma	No	PPPD	I	IV	II	Normal	IDC	TACP
26	68	M	Ph	Carcinoma	No	PPPD	I	IV	II	Normal	IDC	TACP
27	65	M	Pb	Carcinoma	No	DP	I	IV	II	Normal	IDC	TACP
28	76	M	Pb	Carcinoma	No	DP	I	IV	II	Normal	IDC	TACP
29	59	M	Ph	Carcinoma	Yes	PD	II	III	II	CP	IDC	CP
30	75	F	Ph	Carcinoma	Yes	PPPD	II	IV	II	CP	IDC	CP
31	57	F	Ph	TF- pancreatitis	Yes	palliative	II	IV	II	CP	IDC	CP
32	67	M	Ph	TF-pancreatitis	Yes	PD	II	IV	III	CP	IDC	CP
33	79	F	Ph	Carcinoma	Yes	PPPD	III	IV	III	CP	IDC	CP

TIC: time-signal intensity curve; Ph: pancreatic head; Pb: pancreatic body; TF: tumor-forming; PD: pancreaticoduodenectomy; PPPD: pylorus-preserving pancreaticoduodenectomy; DP: distal pancreatectomy; N: normal; IDC: invasive ductal carcinoma; CP: chronic pancreatitis; TACP: tumor-associated chronic pancreatitis.

Table 2 Clinicopathological characteristics and pancreatic TIC profiles in patients with focal pancreatic mass due to chronic pancreatitis

			Location		Underlying		Type of pancreatic TIC of			Histopathology of
Case			of focal	Preoperative	chronic	Operative	proximal	focal	distal	proximal	focal	distal
No.	Age	Sex	mass	diagnosis	pancreatitis	procedure	pancreas	mass	pancreas	pancreas	mass	pancreas
1	70	M	Ph	TF-pancreatitis1	Yes	PPPD	II	II	II	CP	CP	CP
2	55	M	Pb	TF-pancreatitis	Yes	MP	II	II	II	CP	CP	CP
3	62	M	Ph	TF-pancreatitis	Yes	PPPD	II	II	III	CP	CP	CP
4	47	M	Pb	TF-pancreatitis	Yes	DP	II	II	III	CP	CP	CP
5	63	M	Ph	TF-pancreatitis1	Yes	PPPD	III	III	II	CP	CP	CP
6	45	F	Pb	TF-pancreatitis	Yes	DP	III	III	III	CP	CP	CP
7	60	M	Pt	TF-pancreatitis	No	DP	I	II	II	Normal	CP	CP
8	51	F	Pt	TF-pancreatitis	No	DP	I	III	III	Normal	CP	CP

TIC: time-signal intensity curve; Ph: pancreatic head, Pb: pancreatic body, Pt: pancreatic tail; TF: tumor-forming; PPPD: pylorus-preserving pancreaticoduodenectomy; MP: middle pancreatectomy; DP: distal pancreatectomy; CP: chronic pancreatitis;

¹Suspicious of carcinoma.

Table 3 Clinicopathological characteristics and pancreatic TIC profiles in patients with focal pancreatic mass due to islet cell tumor

			Locationof focalmass		Underlyingchronicpancreatitis		Type of pancreatic TIC of			Histopathology of
Case				Preoperative		Operative	proximal	focal	distal	proximal	focal	distal
No.	Age	Sex		diagnosis		procedure	pancreas	mass	pancreas	pancreas	mass	pancreas
1	63	M	Ph	Insulinoma	No	PPPD	I	I	I	Normal	Insulinoma	Normal
2	68	M	Pb	Insulinoma	No	MP	I	I	I	Normal	Insulinoma	Normal
3	82	M	Pb	Islet cell tumor	No	DP	I	I	I	Normal	Glucagonoma	Normal
4	47	F	Pb	Islet cell tumor	No	DP	I	I	I	Normal	Glucagonoma	Normal
5	70	M	Ph	Islet cell tumor	No	DPPHR	I	I	I	Normal	NFICT	Normal
6	46	F	Pb	Islet cell tumor	No	DP	I	I	I	Normal	NFICT	Normal
7	69	F	Pb	Islet cell tumor	No	DP	I	I	I	Normal	NFICT	Normal

TIC: time-signal intensity curve; Ph: pancreatic head, Pb: pancreatic body; PPPD: pylorus-preserving pancreaticoduodenectomy; DPPHR: duodenum-preserving pancreatic head resection; MP: middle pancreatectomy; DP: distal pancreatectomy; NFICT: non-functioning islet cell tumor.