Screening for metronidazole-resistance associated gene fragments of H pylori by suppression subtractive hybridization

Table 1 Homologous analysis of some specific DNA sequences of MTZ-resistant strains

No.	GenBank accession No.	Homolog genes	DNA matches
R1	AE000548	Dipeptide ABC transporter periplasmic dipeptide-binding protein (dppA), S = 433, E = 0.0, I = 554/591	6142-6349
R2	AE000548	Depeptide ABC transporter, permease protein (dppB), S = 433, E = 0.0, I = 554/591	6349-6728
R3	AE000609	Protease (pqqE), S = 273, E = e-151, I = 309/321	9322-9642
R4	AE000579	Ribonuclease III (rnc), S = 216, E = e-117, I = 265/280	10907-11185
R5	AY267368	PHP51, S = 115, E = 4e-57, I = 146/154	3018-3169
R6	AB078638	Replication protein B (REPB), S = 30, E = 2e-06, I = 55/62	1320-1381
R7	AE000633	Ribosomal protein S4 (rps4), S = 354, E = 0.0, I = 406/422	7294-7714
R8	AE000635	predicted coding region HP1334, S = 258, E = e-142, I = 457/523	1529-2050
R9	AE000570	Diaminopimelate epimerase (dapF), S = 215, E = e-116, I = 247/260	7955-8214
R10	AE000599	This region contains an authentic frame shift and is not the result of a sequencing artifact, acetate kinase (ackA), S = 99, E = 4e-47, I = 183/210	8555-8764