Association of serum vascular endothelial growth factor-C and lymphatic vessel density with lymph node metastasis and prognosis of patients with gastric cancer

Table 1 Relationship between SVEGF-C level, expressions of VEGF-C and LVD and pathological features of gastric carcinoma mean ± SD

Pathological characteristics	n	SVEGF-C(ng/L)	VEGF-C		LVD(/200HP)
			+	-
Differentiation degree
G1+G2	36	427.9 ± 130.0	9	27	7.9 ± 0.9
G3	44	733.4 ± 130.0c	41	3a	13.1 ± 2.2c
Depth of invasion
T1+T2	36	536.1 ± 227.4	14	32	9.8 ± 2.8
T3+T4	44	644.9 ± 161.5a	36	8c	11.5 ± 3.2b
LNM
Yes	58	650.9 ± 198.6	46	12	12.0 ± 2.7
No	22	451.0 ± 115.5c	4	18c	7.6 ± 0.5c
Distant metastasis
Yes	11	834.3 ± 80.0	10	1	14.0 ± 1.2
No	69	558.0 ± 187.0c	40	29c	10.2 ± 3.0c
pTNM stage
I+ II	32	412.5 ± 130.0	7	25	7.7 ± 0.9
III+ IV	48	718.2 ± 134.4c	43	5c	12.7 ± 2.4c

^aP < 0.05 differentiation degree of G1 + G2 group and invasion depth of T1 + T2 group;

^bP < 0.01 vs invasion depth of T1 + T2 group;

^cP < 0.001 vs differentiation degree of G1 + G2 group, invasion depth of T1 + T2 group, LNM group, distant metastasis group and pTNM stage of I + II group