Viral Hepatitis
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 28, 2006; 12(8): 1205-1210
Published online Feb 28, 2006. doi: 10.3748/wjg.v12.i8.1205
Table 1 Characteristics of the patients (n, mean±SD)
Type C cirrhosisType C cirrhosissubmitted to splenectomyNon-C cirrhosis
Number172420
Age (yr)62.6 ± 10.663.0 ± 7.161.8 ± 9.5
Gender
Female101510
Male7910
Child’s classification
A11139
B467
C244
Association of HCC475
Table 2 Laboratory findings in the type C cirrhotic and non-C cirrhotic patients (n, mean±SD)
Type C cirrhosisType C cirrhosissubmitted to splenectomyNon-C cirrhosis
RBC (×104/μL)379 ± 61374 ± 65381 ± 63
WBC (/μL)3 652 ± 1 0805 855 ± 1 59513 832 ± 1 048
Platelet (×104/μL)8.2 ± 2.916.1 ± 4.919.2 ± 3.4
> 15.0091
10.0-14.9566
< 9.919213
ALT (IU/L)58.2 ± 25.351.1 ± 35.240.6 ± 23.8
Total bilirubin (mg/dL)1.4 ± 1.20.9 ± 0.312.3 ± 1.8
Albumin (g/L)37 ± 437 ± 634 ± 8
r-globulin (g/L)21 ± 0.522 ± 620 ± 9
IgG (mg/ dL)2 454 ± 693no assay2 220 ± 877
HCV RNA (kcopies/mL)523 ± 403198 ± 2512
Splenic index (cm2)
-196cases5 cases
20-2911cases9 cases
30 – 396 cases5 cases
40-1case3 cases
Table 3 Immunological markers in patients with type C cirrhosis (mean±SD)
Type C cirrhosisType C cirrhosissubmitted to splenectomy
Neopterin (pmol/mL)8.3 ± 3.25.2 ± 2.5b
sIL2R (U/mL)850.7 ± 175.9877.2 ± 458.6
CD4 (%)43.1 ± 8.633.4 ± 7.6
CD8 (%)27.6 ± 7.929.6 ± 9.6
CD4/CD8 ratio1.8 ± 0.91.3 ± 0.4a