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©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Jan 28, 2006; 12(4): 516-519
Published online Jan 28, 2006. doi: 10.3748/wjg.v12.i4.516
Published online Jan 28, 2006. doi: 10.3748/wjg.v12.i4.516
Table 1 Definition of refractory and recurrent ascites according to the consensus of the International Ascites Club[9]
Refractory ascites | cannot be mobilized by diuretics because of a lack of response (mean weight loss less than 200g/d during the last 4 d) or the development of diuretic-induced complications such as hyponatremia, hypokalemia, renal impairment, hepatic encephalopathy, precluding an effective diuretic dosage |
Recidivant ascites | recurs at least on 3 occasions within 1 year despite prescription of dietary sodium restriction and adequate diuretic dosage |
Rossle[11] | Gines[12] | Sanyal[13] | Salerno[14] | |
Patients/selected from pts. | 60/155 | 70/119 | 109/525 | 66/137 |
Complete response (%) | 79 vs 24 | 51 vs 17 | 58 vs 16 | 61 vs 3 |
Survival benefit of TIPS | yes | no | trend | yes |
Number of centers | 2 | ≥5 | 6 | 3 |
Child-Pugh C (%) | 38 | 37 | ? | 76 |
Athyltox. Zirrhose (%) | 79 | 51 | 62 | 42 |
Severe encephalop. (%) | 23 vs 13 | 60 vs 34 | 29 vs 18 | 61 vs 39 |
Mean TIPS Ø (mm) | 9 | 8→10 | 10 | ? |
Table 3 Serum bilirubin concentration at study inclusion and during follow-up (μmol/L, mean±SD)
Table 4 Definition of hepatorenal syndrome according to the consensus of the International Ascites Club[9]
HRS Type 1: Rapidly progressing renal failure (< 2 wk) ≥ 2-fold increase of serum creatinine to > 221μmol/L or 50% decrease of creatinine clearance to < 20mL/min |
HRS Type 2: Not rapidly progressing renal failure |
Serum creatinine > 132.6 μmol/L or |
Creatinine clearance < 40mL/min |
Absence of shock, ongoing bacterial infection, current or recent treatment with nephrotoxic drugs, gastrointestinal or renal fluid loss |
No sustained improvement upon withdrawal of diuretics and plasma volume expansion |
Proteinuria < 0.5g/d, no abnormalities of renal ultrasound |
- Citation: Gerbes AL, Gulberg V. Progress in treatment of massive ascites and hepatorenal syndrome. World J Gastroenterol 2006; 12(4): 516-519
- URL: https://www.wjgnet.com/1007-9327/full/v12/i4/516.htm
- DOI: https://dx.doi.org/10.3748/wjg.v12.i4.516