Association of Fas-670 gene polymorphism with inflammatory bowel disease in Chinese patients

Table 1 Fas-670 genotypes, allele frequencies and carriage rates in healthy controls and inflammatory bowel disease (IBD) in Chinese Han patients.

	Healthy controls (n = 124)	IBD (n = 50)	UC (n = 38)	CD (n = 12)
Genotypes n (%)
AA	41 (33)	15 (30)	12 (32)	3 (25)
AG	64 (52)	21 (42)	15 (40)	6 (50)
GG	19 (15)	14 (28)	11 (28)	3 (25)
Allele frequencies %
A	59	51	51	50
G	41	49	49	50
Carriage %
A	85	72	71	75
G	67	70	68	75

Table 2 Fas-670 genotypes and allele frequencies and location of ulcerative colitis.

	Genotypes n (%)			Allele frequencies (%)
	AA	AG	GG	A	G
Left-sided colitis (n = 20)	7 (35)	7 (35)	6 (30)	52	48
Total colitis (n = 18)	5 (28)	8 (44)	5 (28)	50	50

Table 3 Fas-670 genotypes and allele frequencies in several ethnic healthy controls.

	Genotype frequency n (%)			Allele frequency (%)
	AA	AG	GG	A	G
Chinese (n = 124)	41 (33)	64 (52)	19 (15)	59	41
Dutch (n = 206)[24]	46 (23)	118 (57)	42 (20)	51	49
Australian (n = 183)[25]	46 (25)	97 (53)	40 (22)	52	48
Korean (n = 84)[28]	25 (30)	46 (55)	13 (15)	57	43