Association of polymorphisms of IL and CD14 genes with acute severe pancreatitis and septic shock

Table 1 Comparison of allele frequency between MAP group and SAP group

		MAP (n = 106)	SAP (n = 109)	P
	CC	94	95
IL-1β	CT	12	14
+3 594	TT	0	0
	T allele	12 (5.7)	14 (6.4)	0.74
	GG	0	0
IL-10	AA	75	81
-1 082	GA	31	28
	G allele	31 (14.6)	28 (12.8)	0.592
	CC	62	66
CD-14	TT	14	14
-159	CT	30	29
	T allele	58 (27.4)	57 (26.1)	0.777

Table 2 Comparison of allele frequency between AP and controls

		AP (n = 215)	Controls (n = 116)	P
	CC	189	98
IL-1β	CT	26	18
+3 594	TT	0	0
	T allele	26 (6.0)	18 (7.8)	0.399
	GG	0	0
IL-10	AA	156	79
-1 082	GA	59	37
	G allele	59 (13.7)	37 (15.9)	0.437
	CC	128	71
CD-14	TT	28	13
-159	CT	59	32
	T allele	115 (26.7)	58 (25.0)	0.626

Table 3 Comparison of allele frequency between septic shock and nonseptic shock groups

		Septic shock (n = 33)	Nonseptic shock (n = 76)	P
	CC	27	68
IL-1β	CT	6	8
+3 594	TT	0	0
	T allele	6 (9.1)	8 (5.3)	0.289
	GG	0	0
IL-10	AA	19	62
-1 082	GA	14	14
	G allele	14 (21.2)	14 (9.2)	0.015
	CC	19	47
CD-14	TT	5	9
-159	CT	9	20
	T allele	19 (28.8)	38 (25.0)	0.559

Table 4 Comparison of allele frequency based on different etiologies of SAP (n)%

Allele	Alcoholic SAP (n = 23)	Gallstone SAP (n = 49)	Idiopathic SAP (n = 34)	P
IL-1β+3 594 T	3 (6.5)	6 (6.1)	5 (7.4)	0.952
IL-10-1 082 G	7 (15.2)	12 (12.2)	9 (13.2)	0.886
CD-14-159 T	11 (23.9)	25 (25.5)	21 (30.9)	0.653