Expression of E-cadherin in gastric carcinoma and its correlation with lymph node micrometastasis

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May 28, 2005 (publication date) through Nov 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 28, 2005; 11(20): 3139-3143
Published online May 28, 2005. doi: 10.3748/wjg.v11.i20.3139

Table 1 Correlation between LNM and clinicopathologic characteristics.

Variable	Patients (n)	LNM
Variable	Patients (n)	Negative (%)	Positive (%)	P
Gender
Male	17	9 (52.9)	8 (47.1)
Female	13	7 (53.8)	6 (46.2)	P = 1.000
Age
<50 yr	10	4 (40)	6 (60)
≥R50 yr	20	12 (60)	8 (40)	P = 0.442
Superficial diameter
<5 cm	17	9 (52.9)	8 (47.1)
≥R5 cm	13	7 (53.8)	6 (46.2)	P = 1.000
Tumor location
Upper/middle third	17	8 (47.1)	9 (52.9)
Lower third	13	8 (61.5)	5 (38.5)	P = 0.484
Histologic type
Intestinal	11	9 (81.8)	2 (18.2)
Diffuse	19	7 (36.8)	12 (63.2)	P = 0.026
Depth of invasion
T1/T2	21	14 (66.7)	7 (33.3)
T3/T4	9	2 (22.2)	7 (77.8)	P = 0.046
Histologic differentiation
Well/moderate	13	9 (69.2)	4 (30.8)
Poor	17	7 (58.8)	10 (41.2)	P = 0.159
Lymphatic invasion
Positive	18	7 (38.9)	11 (61.1)
Negative	12	9 (75)	3 (25)	P = 0.072
Vascular invasion
Positive	5	3 (60)	2 (40)
Negative	25	13 (52)	12 (48)	P = 1.000

Table 2 Correlation between the expression of E-cadherin in primary tumors and clinicopathologic characteristics.

Variable	Patients (n)	Expression of E-cadherin
Variable	Patients (n)	Negative (%)	Positive (%)	P
Gender
Male	17	7 (41.2)	10 (58.8)
Female	13	7 (53.8)	6 (46.2)	P = 0.713
Age
<50 yr	10	3 (30)	7 (70)
≥R50 yr	20	11 (55)	9 (45)	P = 0.260
Superficial diameter
<5 cm	17	7 (41.2)	10 (58.8)
≥R5 cm	13	7 (53.8)	6 (46.2)	P = 0.713
Tumor location
Upper/middle third	17	8 (47.1)	9 (52.9)
Lower third	13	6 (46.2)	7 (53.8)	P = 1.000
Histologic type
Intestinal	11	2 (18.2)	9 (81.8)
Diffuse	19	12 (63.2)	7 (36.8)	P = 0.026
Depth of invasion
T1/T2	21	8 (38.1)	13 (61.9)
T3/T4	9	6 (66.7)	3 (33.3)	P = 0.236
Histologic differentiation
Well/moderate	13	2 (15.4)	11 (84.6)
Poor	17	12 (70.6)	5 (29.4)	P = 0.004
Lymph node metastasis
Positive	18	12 (66.7)	6 (33.3)
Negative	12	2 (16.7)	10 (83.3)	P = 0.011
Lymphatic invasion
Positive	18	13 (72.2)	5 (27.8)
Negative	12	1 (8.3)	11 (91.7)	P = 0.001

Table 3 Correlation between LNM and the expression of E-cadherin.

Citation: Wu ZY, Zhan WH, Li JH, He YL, Wang JP, Lan P, Peng JS, Cai SR. Expression of E-cadherin in gastric carcinoma and its correlation with lymph node micrometastasis. World J Gastroenterol 2005; 11(20): 3139-3143
URL: https://www.wjgnet.com/1007-9327/full/v11/i20/3139.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i20.3139